systemic therapy Clinical Research Trials

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Found 287 clinical trials

Targeted Biopsy of Carbon Nanoparticles Labelled Axillary Node for cN+ Breast Cancer

To explore the feasibility of target biopsy of carbon nanoparticles labelled lymph node after neoadjuvant systemic therapy for cN+ breast cancer, and evaluate whether it can accurately predict

0 views
30 Jan, 2021
1 location

SinTilimab After Radiation (STAR Study)

This is a single-arm phase II study, to investigator the efficacy and safety of sintilimab after radiation in advanced NSCLC, who had failed first line systemic therapy.

cancer chemotherapy

progressive disease

systemic therapy

metastasis

EGFR

0 views
23 Jan, 2021
1 location

Vactosertib in Combination With Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects

-L1 positive, non-small cell lung cancer (NSCLC) who have not previously received systemic therapy for advanced disease and in whom EGFR, ALK, BRAF, ROS1-directed therapy is not indicated.

0 views
29 Jan, 2021
1 location

A Non-Randomized Study of Internal Radiation Therapy to the Liver in Patients With Primary Liver Cancer for Whom Surgery is Not Possible.

material directly to neoplastic tissue in the liver. Systemic therapy is largely ineffective.

hepatoma

therasphere

primary liver cancer

serum bilirubin

18 views
07 Nov, 2020
1 location

A Phase II Study of HMPL-504 in Lung Sarcomatoid Carcinoma and Other Non-small Cell Lung Cancer

mutation. The targeted population is the patients with MET Exon 14 mutation who have failed prior systemic therapy (ies), or are unwilling or can not tolerate to receive chemotherapy. Pathological

32 views
24 Jan, 2021
2 locations

Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC

hepatocellular carcinoma who could not be radically cured and not receive any prior systemic therapy. The study will use PFS and OS as the co-primary endpoints, with approximately 280 patients planned to be

0 views
03 Feb, 2021
1 location

Study of Sorafenib and Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)

local or systemic therapy for advanced HCC and the available therapies for advanced unresectable and/or metastatic HCC have limited clinical values, with low response rates and little impact

coumadin

gemcitabine

neutrophil count

measurable disease

systemic therapy

14 views
07 Nov, 2020
1 location

A Clinical Trial of Stereotactic Ablative Radiotherapy for Metastatic Lymphadenopathy

metastases. No specific treatment modality has been established as the standard therapy. Systemic therapy is usually considered since lymphadenopathy is considered as a sign of disease dissemination though

6 views
22 Jan, 2021
1 location

A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis

one or both eyes. Scleritis may results in vision threatening ocular complications, if left untreated. Treatment of scleritis is usually chronic and requires systemic therapy with non-steroidal anti

1 views
25 Jan, 2021
5 locations

HMPL-453 in Advanced Malignant Mesothelioma

This is a phase II, single arm, multicenter and open-label study to evaluate the efficacy, safety and pharmacokinetic of HMPL-453 in patient with advanced Malignant Mesothelioma

0 views
24 Jan, 2021
1 location

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Found 287 clinical trials