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Found 160 clinical trials
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A phase 3, randomized, placebo-controlled study to assess the efficacy and safety of an investigational medication versus placebo in patients with systemic sclerosis

A phase 3, randomized, placebo-controlled study to assess the efficacy and safety of an investigational medication versus placebo in patients with systemic sclerosis

  • 1104 views
  • 23 Nov, 2020
  • 1 location
featured
A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation

A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation

  • 94 views
  • 08 Nov, 2020
  • 1 location
featured
A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

  • 74 views
  • 25 Mar, 2021
  • 1 location
A Comparison of Intra-operative Radiotherapy Boost With External Beam Radiotherapy Boost in Early Breast Cancer.

TARGIT-Boost is an international randomised clinical trial designed to test the hypothesis that the tumour bed boost delivered as a single dose of targeted intraoperative radiotherapy (TARGIT-B) is superior to the conventional course of external beam radiotherapy boost (EBRT-Boost), especially in women with high risk of local recurrence. It is …

  • 289 views
  • 22 Jan, 2021
  • 42 locations
Platelet Gel in Systemic Sclerosis

- Systemic sclerosis (scleroderma; SSc) is a connective tissue disease characterized by a progressive fibrosis of the skin and visceral organs. - A diffuse cutaneous

progressive systemic sclerosis
rheumatism
fibrosis
prostacyclin
endothelin
  • 24 views
  • 07 Nov, 2020
  • 1 location
Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement

The purpose of this study is to verify effect and tolerability of imatinib on pulmonary and skin fibrosis in patients affected by systemic sclerosis.

progressive systemic sclerosis
pulmonary involvement
alveolitis
fibrosis
imatinib
  • 33 views
  • 07 Nov, 2020
  • 1 location
The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome

To evaluate the effectiveness and safety of tacrolimus eye drops (FK-506) in the treatment of Posner-Schlossman Syndrome. It is expected to collect 30 patients with PSS who are in the

  • 0 views
  • 03 May, 2021
  • 1 location
Pilot Study of the Effect of Laser on Reversing Chronic Radiation Injury

underlying fibrotic process can help restore normal skin functions in patients affected with chronic radiation dermatitis (RD) and other debilitating fibrotic diseases in dermatology such as scleroderma

  • 0 views
  • 23 Jan, 2021
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Pulmonary Arterial Hypertension or PAH is a progressive condition for which there is no cure. Even with substantial pharmacologic advances in the modern treatment era, survival still remains unacceptably poor, as reported in large PAH registries. Preclinical studies suggest that the administration of allogeneic CDCs have the potential to reduce …

  • 96 views
  • 25 Mar, 2021
  • 1 location
Psychiatric Symptoms in Employees Experiencing High Levels of Stress Before and After the Intake of Probiotics

Sub-project 1 Background:With the increasing number of shift workers required for social and economic activities, increasing prevalence of metabolic diseases has been found in this group of people. Although reasons for this include reduced physical activity owing to unfixed working hours, lack of sleep or disturbances in the circadian rhythm …

  • 0 views
  • 01 Mar, 2021
  • 1 location