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Found 482 clinical trials
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

antihypertensive therapy
renal angiogram
hypertension
hypertensive medication
angiography
  • 897 views
  • 10 Sep, 2021
  • 83 locations
featured
C1071003 MagnetisMM-3

The purpose of the study is to evaluate whether single-agent PF-06863135 can provide clinical benefit in participants with relapsed/refractory multiple myeloma. PF-06863135 is a bispecific antibody: binding of PF-06863135 to CD3-expressing T-cells and BCMA-expressing multiple myeloma cells causes targeted T-cell-mediated cytotoxicity.

refractory multiple myeloma
  • 1 views
  • 23 Sep, 2021
  • 5 locations
featured
A Research Study for Pentalogy of Cantrell

This study will collect blood, urine, and other tissue samples from patients with Pentalogy of Cantrell (POC) and other inherited diseases that may involve mutations in non-muscle myosin II-B heavy chain (MYH10). We will also collect samples from the relatives of affected individuals. POC is a very rare disorder in …

nervous system disease
congenital disorders
nervous system disorders
  • 17 views
  • 22 Dec, 2020
  • 1 location
featured
Phase 1/2 Study Of Intratumoral G100 With Or Without Pembrolizumab or Rituximab In Patients With Follicular Non-Hodgkin’s Lymphoma

This is a multi-center Phase 1/2 open label trial of intratumoral G100 in patients with low grade NHL. Patients with NHL will be enrolled and receive G100 to an accessable tumor mass. Clinical response will be evaluated in the injected lesion and systemic (abscopal) responses will be evaluated in distal …

non-hodgkin's lymphoma
lymphomas
lymphoma
  • 73 views
  • 22 Dec, 2020
  • 31 locations
A Study of Nal-IRI With 5-FU Levofolinic Acid and Oxaliplatin in Patients With Resectable Pancreatic Cancer

Rational:Pancreatic cancer is a systemic disease at the time of diagnosis, even among patients with apparent localized disease. Surgical resection is the only potentially curative therapy for

irinotecan
leucovorin
cancer
celiac
folfirinox
  • 3 views
  • 08 Aug, 2021
  • 1 location
OMEGA Local Ablative Therapy in Oligometastatic NSCLC

Oligometastatic lung cancer (OM-NSCLC) seems to be associated with a better prognosis than usual Stage IV non-small cell lung cancer when radical local therapy of all metastatic sites is administered but the impact of such an approach on overall survival and quality of life remains to be defined by adequately …

brain metastases
carboplatin
metastasis
EGFR
lung carcinoma
  • 0 views
  • 23 Jan, 2021
  • 1 location
Study of Intra-Arterial Oxaliplatin Plus Capecitabine to Treat Liver Metastases From Colorectal Cancer

The treatment proposed in this trial is to administer intra-arterial chemotherapy to liver metastases from colorectal cancer when the blood flow to and from the liver has been isolated via balloon catheters through a vascular access system called the AVAS. The objective of this study is to evaluate the tumour …

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Bilateral Premolar Extraction vs Distalization: A Randomised Clinical Trial

Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable. Treatment of class II malocclusion due to maxillary protrusion can be done with bilateral maxillary first premolar extraction followed by en-masse retraction of …

  • 0 views
  • 18 Feb, 2021
  • 1 location
Assessment of TetraSOD Efficacy to Improve Semen Parameters in Men With Idiopathic Infertility

TetraSOD is a unique marine phytoplankton (Tetraselmis chuii) SOD-rich ingredient that is grown under patent-protected technology exclusively designed by the company Fitoplancton Marino, S.L. (Spain). In a previous pilot trial, the ability of TetraSOD to improve semen characteristics in idiopathic infertile men after three months of treatment was assessed, revealing …

  • 0 views
  • 10 Sep, 2021
  • 1 location
Efficacy of Palliative Low-Dose Involved-Field Radiation Therapy for Recurrent Advanced Follicular Lymphoma

Many trials that patients with advanced or recurrent indolent lymphoma managed with very low-dose (4Gy) limited-field RT (LD-IFRT) have shown that high response rates and durable remission can be achieved. However, the results of two phase III trials have failed to demonstrate the lasting response rate (RR) with LD-IFRT versus …

  • 7 views
  • 21 Jan, 2021
  • 1 location