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Found 31 clinical trials
Transcatheter Aortic Valve Replacement Single Center Registry in Chinese Population

The purpose of this study is to evaluate the safety and effectiveness of transcatheter aortic valve replacement in Chinese population.

  • 21 Jul, 2021
  • 1 location
Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation

Evaluation of TAVR using the NAVITOR valve in a Global Investigation.

  • 22 Aug, 2021
  • 3 locations
Evolut PRO China Clinical Study

Interventional study to evaluate the safety and efficacy of the Medtronic CoreValve Evolut PRO System when used by China implanting centers in Chinese patients with severe symptomatic aortic

  • 08 Sep, 2021
  • 1 location
A Two -Stage First in Human (FIH) Feasibility / Pivotal Study of the Vienna Aortic Valve SE System

This is a prospective, non-randomized, single arm, multicenter, multinational two-stage FIH feasibility followed by pivotal study in symptomatic patients with severe aortic stenosis.

  • 28 Jun, 2021
  • 7 locations
Platelet REACtivity According to TICagrelor Dose After Transcatheter AorticValve Implantation

The narrowing of the aortic valve, which prevents blood from reaching the entire body correctly is a common disease in our environment. To correct this problem, many patients undergo Transcatheter Aortic Valve Implantation (TAVI) according to standard clinical practice. Patients have to continue with a specific pharmacological treatment (antiplatelet agents) …

  • 05 Aug, 2021
  • 1 location
Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis

Abundant evidence suggests that Angiotensin Converting Enzyme (ACE) inhibition potentially could reduce the hazardous effects of aortic stenosis and improve haemodynamics. The treatment seems safe even in patients with severe stenosis. There are however no randomised clinical trials that can confirm this hypothesis.

angina pectoris
symptomatic aortic stenosis
  • 07 Nov, 2020
  • 1 location
The Potential of Candesartan to Retard the Progression of Aortic Stenosis

The present study defines a blinded, randomized, placebo-controlled, prospective study, the aim of which is to determine the influence of effective treatment with Type 1 angiotensin II (Ang II) receptor (AT-1R) antagonist, using candesartan (target dose 16 mg) on stenotic aortic valves. The investigators will specifically quantify whether candesartan attenuates …

angiotensin ii
  • 07 Nov, 2020
  • 1 location
Sedation or General Anesthesia During TAVR

Transcatheter aortic valve replacement TAVR is become the reference method for patients with severe aortic stenosis who are contraindicated or at risk for surgical aortic replacement. Initially performed under general anesthesia (GA), recent developpement of minimalist approach of TAVR include the use of local anesthesia (LA) with or without conscious …

  • 28 Jan, 2021
  • 1 location
Chronic Recurrent Multifocal Osteomyelitis - a Bacterial Cause?

Chronic recurrent multifocal osteomyelitis (CRMO) is an immune-mediated chronic inflammatory self- limiting disease with non-suppurative inflammation involving one or multiple bone foci. A bacterial etiology has not yet been proven, but the investigators hypothesize that CRMO is caused by chronic infection. Using existing knowledge of chronic infections combined with sensitive …

  • 27 Jan, 2021
  • 1 location
Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial

treatment of severe symptomatic aortic stenosis via transfemoral and alternative delivery methods in high risk and extreme risk patients.

symptomatic aortic stenosis
  • 29 Jan, 2021
  • 70 locations