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Found 43 clinical trials
Neurologic Stem Cell Treatment Study (NEST)

This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. …

nervous
  • 409 views
  • 26 Apr, 2022
  • 3 locations
The Effect of Hericium Erinaceus Mycelium in Non-motor Symptoms of Parkinson's Disease

Parkinson disease (PD) is considered a multisystemic neurodegenerative disorder, together with the classic motor disability, and a number of non-motor symptoms (NMS).NMS have a significant negative relation with patients' quality of life. In general, both medicinal and nonmedicinal therapies are often advised for PD patients with NMS, but robust evidences …

motor symptoms
cognitive decline
neurodegenerative disorders
parkinsonism
  • 11 views
  • 25 Jan, 2022
  • 1 location
Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

The study is designed to determine the relationship between structural and functional changes in the brain on imaging and progression of speech and language, neurological and neuropsychological features in patients with neurodegenerative apraxia of speech (AOS).

  • 19 views
  • 24 Jan, 2022
  • 1 location
The MOTIVE-PSP Initiative (Progressive Supranuclear Palsy)

Progressive Supranuclear Palsy (PSP) is a rapidly progressive neurodegenerative disease characterized by falls and oculomotor disturbances. Several clinical trials are currently evaluating the

early diagnosis
  • 0 views
  • 22 Mar, 2022
  • 1 location
Remote Monitoring in Progressive Supranuclear Palsy (PSP)

This is a single-arm, longitudinal, observational study on the use of wearable sensors and digital health technology to measure fall frequency and motor, speech, and cognitive function in patients with PSP over the course of approximately one year. Participants will perform supervised remote assessments monthly and in-person assessments approximately every …

  • 0 views
  • 10 Mar, 2022
  • 2 locations
Image Characteristic and Longitudinal Follow up of 18F-PMPBB3 (APN-1607) PET for Progressive Supranuclear Palsy

The study will enroll 20 PSP and 8 normal subjects with complete neurological examination, 18F-PMPBB3 (APN-1607) PET and MRI assessment. To explore: (1) whether 18F-PMPBB3 (APN-1607) can detect the 4R tau protein in the brain of PSP patients; (2) whether 18F-PMPBB3 (APN-1607) can distinguish the clinical characteristics of PSP; (3) …

tau protein
screening procedures
Accepts healthy volunteers
cognitive assessment
  • 0 views
  • 26 Jan, 2022
  • 1 location
Saliva and Extracellular Vesicles for Parkinson's Disease (RaSPiD)

Rehabilitation is crucial in the treatment of people with Parkinson's disease (PD) as it can ameliorate motor and non-motor impairments, improving their clinical profile and quality of life. Considering the complex biological processes occurring in PD brain, the identification of accessible and measurable biomarkers to monitor the events induced by …

Accepts healthy volunteers
  • 0 views
  • 21 Apr, 2022
PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK (PROSPECT-M)

Progressive Supranuclear Palsy (PSP), Cortico-Basal Degeneration (CBD) and Multiple System Atrophy (MSA) are degenerative brain conditions for which there are currently no curative treatments

Accepts healthy volunteers
early diagnosis
progressive supranuclear palsy
parkinson's disease
parkinsonism
  • 505 views
  • 25 Jan, 2022
  • 1 location
Systematic Assessment of Laryngopharyngeal Function in Patients With MSA, PD, and 4repeat Tauopathies (FEEMSA)

multiple system atrophy (MSA), Parkinson's disease (PD) and progressive supranuclear palsy (PSP) and related 4repeat tauopathies. The results of a fiberoptic / flexible endoscopic evaluation of swallowing

tauopathies
supranuclear palsy
parkinson's disease
atrophy
cognitive assessment
  • 0 views
  • 26 Jan, 2022
  • 8 locations
Neurodegenerative Diseases Registry (NDD Registry)

progressive supranuclear palsy (PSP). Similarly, distinguishing AD from other dementia syndromes including frontotemporal dementia (FTD), dementia with Lewy Bodies (DLB), corticobasal degeneration (CBD) and

Accepts healthy volunteers
vascular dementia
progressive supranuclear palsy
parkinson's disease
drug trials
  • 129 views
  • 26 Jan, 2022
  • 1 location