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Found 43 clinical trials
Featured trial
New Approaches to Dementia Heterogeneity.

This study is looking for adults who have mild cognitive impairment, Alzheimer’s, or other forms of dementia. The study is also looking for people with normal cognition, as a comparison. The study is interested in the ways that brain function changes over time with the goal of improving the ability to diagnose …

cancer
stroke
heart disease
multiple sclerosis
dementia
  • 149 views
  • 25 May, 2021
  • 1 location
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy

This is a phase 1, multi-center, double-blind, placebo-controlled, multiple dose escalation study with NIO752 in progressive supranuclear palsy (PSP) participants.

dopamine
screening procedures
gaze palsy
levodopa
coenzyme q
  • 14 views
  • 10 Mar, 2022
  • 11 locations
Epidemiology and Pathophysiology of Parkinsonism in the Caribbeans

The primary aim of this study is to estimate the frequency and to characterize clinically atypical parkinsonism in the French West Indies and Guyana.

  • 0 views
  • 21 Jan, 2021
  • 2 locations
RT001 in Patients With Progressive Supranuclear Palsy (PSP) PROGRESSIVE SUPRANUCLEAR PALSY

This is a randomized, placebo-controlled trial of RT001 in patients with PSP.

  • 0 views
  • 26 Jan, 2022
  • 1 location
A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy

This study is designed to learn more about overall tau burden in the brain of patients with Progressive Supranuclear Palsy (PSP).

Accepts healthy volunteers
cognitive assessment
  • 101 views
  • 25 Jan, 2022
  • 1 location
Efficacy of RIVAstigmine on Motor, Cognitive and Behavioural Impairment in Progressive Supranuclear Palsy (RIVA-PSP)

Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease from the parkinsonian syndrome group. It represents 5 to 10% of all parkinsonian syndromes and affects 3,000 to 10,000

parkinsonism
screening procedures
parkinson's disease
donepezil
dopa
  • 203 views
  • 23 Feb, 2022
  • 1 location
A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP)

This is a Phase 2a study to assess the safety and tolerability of TPN-101 patients with PSP.

  • 13 views
  • 13 May, 2022
  • 10 locations
Test-retest Study With [18F]PI-2620 in PSP-RS and NDC

The overall goal of this protocol is to evaluate the imaging characteristics of [18F]PI-2620 using positron emission tomography (PET) in patients with progressive supranuclear palsy

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 1 location
Spinal Cord Stimulation Therapy for Freezing of Gait in Parkinson's Syndrome Patients

Spinal cord stimulation may be a new therapeutic approach for freezing of gait. It's a multi-center, prospective, open label clinical study with a 12 months follow-up period, to investigate the therapeutic effect and safety of spinal cord stimulation for freezing of gait in patients with advanced Parkinson's disease and Parkinsonism-Plus …

  • 0 views
  • 28 Jan, 2021
  • 1 location
Trial of Parkinson's And Zoledronic Acid (TOPAZ)

This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will …

parkinsonism
osteoporosis
screening procedures
parkinson's disease
cognitive assessment
  • 256 views
  • 12 May, 2022
  • 53 locations