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Found 5 clinical trials
Therapeutic Instillation of Mistletoe (TIM)

The aim of this phase III study is to assess the efficacy of abnobaVISCUM® 900 compared with Mitomycin C (MMC) monotherapy in patients with superficial bladder carcinoma by evaluation of the time to tumor recurrence. Secondary objective is to evaluate the safety of abnobaVISCUM® 900, in particular, to compare the …

  • 13 May, 2022
  • 23 locations
EG-70 in NMIBC Patients Who Are BCG-Unresponsive and High-Risk NMIBC Patients Who Have Been Incompletely Treated With BCG or Are BCG-Naïve (LEGEND STUDY)

This open-label, multicenter study will evaluate the safety and efficacy of intravesical administration of EG-70 and its effect on bladder tumors in patients with NMIBC who have failed BCG therapy and are recommended for radical cystectomy or high-risk NMIBC patients who are BCG-naïve or have received incomplete BCG treatment. This …

  • 23 May, 2022
  • 8 locations
Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer (TROJAN)

A multi-center, open-label, phase II clinical study of metformin in up to evaluable 49 patients with low-grade NMIBC with the aim to determine the overall response to administration of oral metformin for 3 months in a marker tumour deliberately left following transurethral resection of multiple, papillary NMIBC tumours.

bladder carcinoma
carcinoma in situ
transitional cell carcinoma
  • 23 Feb, 2022
  • 1 location
RESECT: Improving Quality in TURBT Surgery. (RESECT)

Superficial bladder cancer, known as non-muscle-invasive bladder cancer (NMIBC), is the most common type of bladder cancer. It is expensive to manage and significantly impacts on patients

transurethral bladder excision
cancer recurrence
invasive bladder cancer
bladder tumor
  • 24 May, 2022
  • 1 location
Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer

The purpose of this study is to determine if analysis of DNA and protein material found in urine will be useful in the detection of urothelial cancer of the bladder and kidney. This analysis may be helpful to determine if how a particular cancer will act regarding remission and recurrence

bladder cancer
primary cancer
bladder tumor
  • 23 Jan, 2022
  • 1 location