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Found 58 clinical trials
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A Multicenter, Open-Label, Randomized, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib in Combination with Everolimus or Pembrolizumab Versus Sunitinib Alone in First Line Treatment of Subjects with Advanced Renal Cell Carcinoma

A Multicenter, Open-Label, Randomized, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib in Combination with Everolimus or Pembrolizumab Versus Sunitinib Alone in First Line Treatment of

  • 220 views
  • 08 Nov, 2020
  • 1 location
featured
Alliance A031203: Randomized Phase II Study Comparing Cabozantinib (NSC #761968 and IND #116059) With Commercially Supplied Sunitinib in Patients With Previously Untreated Locally Advanced or Metastatic Renal Cell Carcinoma

Alliance A031203: Randomized Phase II Study Comparing Cabozantinib (NSC #761968 and IND #116059) With Commercially Supplied Sunitinib in Patients With Previously Untreated Locally Advanced or

  • 186 views
  • 08 Nov, 2020
  • 1 location
featured
Prostate Cancer

Prostate Cancer

  • 72 views
  • 08 Nov, 2020
  • 1 location
Sunitinib and Radiation in Patients With Resectable Soft-tissue Sarcoma

radiotherapy. Sunitinib is a new drug that is active against cells with low oxygen levels. The combination of sunitinib and radiotherapy has shown promising results in other cancers. The purpose of

cancer
  • 12 views
  • 07 Nov, 2020
  • 1 location
Sunitinib as First-Line Therapy in Treating Patients With Locally Advanced Metastatic Papillary Renal Cell Cancer

RATIONALE: Sunitinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is

measurable disease
platelet count
carcinoma
metastasis
sunitinib
  • 27 views
  • 07 Nov, 2020
  • 13 locations
Salvage Therapy With Sunitinib Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer

Sunitinib shows anti-tumor activity in a variety of human non-small cell lung tumor ex vivo models. Many Phases II and III clinical trials of sunitinib in several solid tumors are

cancer chemotherapy
measurable disease
lung carcinoma
bevacizumab
carcinoma
  • 2 views
  • 08 Nov, 2020
  • 1 location
A Study of Abemaciclib in Combination With Sunitinib in Metastatic Renal Cell Carcinoma

The purpose of this study is to determine the safety, tolerability, and maximal tolerated dose (MTD) of the combination of Abemaciclib and Sunitinib administered orally in patients with advanced

  • 8 views
  • 12 Dec, 2020
  • 1 location
A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule Versus Sunitinib in Subjects With Advanced Renal Cancer

This study is a randomized, positive parallel controlled, multicentre phase III clinical trial to evaluate the efficacy and safety of TQB2450 combined with anlotinib versus sunitinib in subjects

  • 0 views
  • 25 Jan, 2021
  • 26 locations
Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure

of imatinib and sunitinib.

  • 0 views
  • 25 Jan, 2021
  • 7 locations
Topical Sildenafil as Pre-Treatment for Hand-Foot Skin Reaction

with the targeted agents sorafenib and sunitinib. This project proposal aims to conduct an open-label pilot study to assess whether pre-medication with this cream can be an effective way of preventing

  • 1 views
  • 25 Jan, 2021
  • 2 locations