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Found 9 clinical trials
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Are you a type 2 diabetic between 30 and 70 years of age and currently being treated with either Metformin alone or Metformin in combination with Sulfonylurea such as Glyburide (Diabeta), Glipizide (Glucotrol), Repaglinide (Prandin)?

Are you a type 2 diabetic between 30 and 70 years of age and currently being treated with either Metformin alone or Metformin in combination with Sulfonylurea such as Glyburide (Diabeta), Glipizide

  • 94 views
  • 08 Nov, 2020
  • 1 location
featured
Do you have Type 2 Diabetes? We are enrolling adult volunteers now.

Do you have Type 2 Diabetes? We are enrolling adult volunteers now.

  • 18 views
  • 08 Nov, 2020
  • 1 location
featured
Diabetes /Adolescent Type 2 diabetes.

Diabetes /Adolescent Type 2 diabetes.

  • 74 views
  • 08 Nov, 2020
  • 1 location
The Effect of Sitagliptin on Hypertension Arterial Stiffness Oxidative Stress and Inflammation

Recently a new category of antihyperglycemic therapy aiming to modulate the incretin system has emerged. These drugs induce insulin secretion without inducing hypoglycemia. The effect of the incretin modulators drugs on hypertension, arterial stiffness, inflammation and oxidative stress parameters have not been fully investigated yet.GLP-1 analogue has been suggested to …

heart disease
type 2 diabetes mellitus
arterial stiffness
hypertension
sitagliptin
  • 11 views
  • 07 Nov, 2020
  • 1 location
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)

The main reason for this study is to compare the study drug tirzepatide to insulin glargine in participants with type 2 diabetes on metformin with or without a sulfonylurea.

body mass index
metformin
sulfonylurea
type 2 diabetes mellitus
hemoglobin a1c
  • 94 views
  • 27 Jan, 2021
  • 103 locations
Lanifibranor in Patients With Type 2 Diabetes & Nonalcoholic Fatty Liver Disease

The primary aim is to establish the safety, efficacy and mechanism of action of lanifibranor in patients with type 2 diabetes (T2DM) and nonalcoholic fatty liver disease (NAFLD). Specifically, to determine if lanifibranor decreases intrahepatic triglycerides (IHTG) (primary endpoint), improves hepatic insulin sensitivity, endogenous (hepatic) glucose production, de novo lipogenesis …

type 2 diabetes mellitus
neutrophil count
metformin
sulfonylurea
MRI
  • 13 views
  • 24 Jan, 2021
  • 1 location
Cancer in Patients on Dapagliflozin and Other Antidiabetic Treatment

females who are new users of antidiabetic drugs (ADs) in classes other than sodium-glucose cotransporter 2 (SGLT2) inhibitors, insulin monotherapy, metformin monotherapy, or sulfonylurea monotherapy and

cancer
metformin
bladder cancer
bladder tumor
  • 0 views
  • 27 Jan, 2021
  • 4 locations
Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease

This is a proposal for a retrospective observational study of the safety of metformin use in patients with chronic kidney disease, compared to other commonly used diabetes drugs. It will be conducted using retrospective data from the New York City CDRN, Medicare administrate files, and New York State Medicaid administrative …

type 2 diabetes mellitus
nephropathy
diabetes
antidiabetics
sglt2 inhibitor
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Substitution of Sulfonylureas With New Generation of Hypoglycemic Drugs for the Treatment of Type 2 Diabetes Mellitus

This is a multicentric, prospective, parallel groups study. Patient recruitment will be carried out at the U.O. Departmental Endocrinology and Diabetology ASST FBF Sacco, Fatebenefratelli and Ophthalmic Hospital, and at the SSD of Endocrine Diseases and Diabetology ASST FBF Sacco, L. Sacco Hospital. At the screening visit, patients being treated …

active treatment
renal function
diabetes
  • 0 views
  • 26 Jan, 2021
  • 1 location