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Found 4 clinical trials
The Role of Tofacitinib in Steroid Withdrawal in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a systemic chronic arthritis characterized by systemic inflammation, persistent synovitis and final joint destruction Inflammatory diseases can lead to decreased productivity and impaired health-related quality of life. As a chronic disease, rheumatoid Chronic arthritis needs long-term treatment. At the same time, RA can cause skin, eye, …

DMARD
tofacitinib
antirheumatics
synovitis
stiffness
  • 8 views
  • 22 Jun, 2021
  • 1 location
Double Blind Trial Investigating the Role of Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients

lowering the doses of opioids needed and lowering side effects. Sulfasalazine poses such quality it is a safe anti-inflammatory drug with established safety profile. It has been in use for over 50 years

  • 0 views
  • 20 Oct, 2022
  • 2 locations
Clinical Trial Evaluating Methotrexate or Leflunomide + Targeted Therapy Versus Methotrexate or Leflunomide + Sulfasalazine + Hydroxychloroquine in Patients With Rheumatoid Arthritis and Insufficient Response to Methotrexate or Leflunomide (BIO3)

Approximately, 40 to 50% of patients with rheumatoid arthritis (RA), the most frequent inflammatory arthritide, are non responders to the consensual 1st line of treatment : methotrexate. In these patients, it is well demonstrated that the addition of other immunomodulatory drug(s) often results in a significant improvement. However, the best …

abatacept
hydroxychloroquine
tocilizumab
methotrexate
tofacitinib
  • 0 views
  • 04 Oct, 2022
  • 1 location
Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial (SPEED)

SPEED is a three arm interventional trial nested within a cohort (Trials Within Cohorts or TWiCs design). This tests more aggressive early therapy in patients newly diagnosed with moderate to severe PsA. Arm 1 will receive standard step up therapy in the cohort and act as the control group. Arm …

arthritis
methotrexate
leflunomide
rheumatic diseases
anti-rheumatic drugs
  • 2 views
  • 02 Jun, 2022
  • 1 location