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Found 109 clinical trials
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Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

The PROTECT-ICD trial is a physician-led, multi-centre randomised controlled trial targeting prevention of sudden cardiac death in patients who have poor cardiac function following a myocardial

  • 123 views
  • 18 Oct, 2021
  • 37 locations
None
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

  • 44 views
  • 30 Nov, 2021
  • 293 locations
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A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing

This study will test the hypothesis that implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) without performing a defibrillation test is non-inferior to S-ICD implant with a defibrillation test with regards to the primary endpoint failed first shock in a spontaneous arrhythmia episode when implant position is confirmed with PRAETORIAN …

  • 79 views
  • 25 Jan, 2021
  • 41 locations
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Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac Resynchronisation Therapy, the implantation of a pacemaker (index group) is not inferior to defibrillator (control group) with respect to all-cause mortality.

cardiomyopathy
medical therapy
cardiac resynchronization therapy
ejection fraction
  • 2 views
  • 15 Nov, 2021
  • 360 locations
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Influence of Sacubitril/Valsartan on Autonomic Cardiac Nervous System in Heart Failure Patients: an Exploratory Study

failure with reduced ejection fraction show impaired heart rate variability, knowing that in these patients such impairment is highly associated with an increased risk of sudden cardiac death. In

  • 0 views
  • 26 Jan, 2021
  • 1 location
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Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis

, lymph nodes and the heart. In this latter case, cardiac sarcoidosis (CS) can lead to atrioventricular (AV) blocks, ventricular arrhythmias, heart failure (HF) and sudden cardiac death. Similar to other

  • 7 views
  • 16 Nov, 2021
  • 2 locations
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Prospective Multicenter Study on Mitral Annular Disjunction

Observational cohort prospective multicenter study on patients with mitral annular disjunction (MAD). MAD is defined as a separation (1 mm) between the atrial wall-mitral valvular junction and the left ventricular free wall during end-systole

  • 0 views
  • 23 Jun, 2021
  • 1 location
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The Nordic Baltic Chronic Total Occlusion (CTO) Arrhythmia Study

In patients with a chronic total coronary occlusion (CTO ), clinically significant arrhythmia seems to be an important and a poorly investigated problem. The arrhythmia prevalence in an all-comer CTO-population is unknown, but in ICD-populations with ischemic heart disease, a CTO may be found in half of patients with life-threatening …

  • 0 views
  • 18 Mar, 2021
  • 1 location
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Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial

The current standard of care for ventricular tachycardia (VT) includes the use of medicine called anti-arrhythmic drugs (AADs) and Implantable Cardioverter Defibrillator (ICD) therapy. These treatments are used to terminate the irregular heartbeats and bring the heart back to a normal rhythm. Catheter ablation is a procedure used to eliminate …

  • 0 views
  • 22 Jan, 2021
  • 11 locations
None
RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy

This is a prospective multicentric Italian study to evaluate the arrhythmic risk in myotonic dystrophy type 1.

  • 19 views
  • 07 Nov, 2020
  • 1 location