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Found 6 clinical trials
Subconjunctival Bevacizumab to Prevent Bleb Failure After Glaucoma Filtration Surgery

This study analyzes the safety and efficacy of off-label Subconjunctival Injection of bevacizumab (Avastin) versus 0.02% mitomycin C (MMC) for preventing bleb failure following glaucoma

cataract
subconjunctival injection
filtration surgery
angle closure glaucoma
mitomycin
  • 28 views
  • 07 Nov, 2020
  • 1 location
Subconjunctival Injection of Local Anesthetic in Anterior Blepharoptosis Repair

chalazion incision and drainage and full-thickness eyelid resections. The purpose of this study is to determine whether an additional subconjunctival injection of local anesthetic, through the posterior

ptosis repair
incision and drainage
xylocaine
discomfort
brimonidine tartrate ophthalmic solution
  • 3 views
  • 01 Jun, 2021
  • 2 locations
Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in Trabeculectomy

In this Pilot explorative study, the investigators are going to estimate and compare the outcomes of three different delivery methods of MMC for Trabeculectomy: a subconjunctival injection of

  • 0 views
  • 27 Jan, 2021
  • 4 locations
Safety of Locally Delivered Allogeneic Mesenchymal Stromal Cells

This study is a longitudinal assessment using a classic dose-escalation study design to assess the safety and maximal tolerated dose (MTD) of locally delivered allogeneic mesenchymal stromal cells (MSC) for promoting corneal repair. The study will be conducted at Illinois Eye and Ear Infirmary located at University of Illinois at …

  • 0 views
  • 06 Aug, 2021
  • 1 location
Intravitreal Adalimumab in Refractory Diabetic Retinopathy Choroidal Neovascularization or Uveitis: A Pilot Study

Direct intravitreal administration of medication is the preferred method of treatment for uveitis and retinal vascular disorders. The eye is a self contained organ relatively isolated from the systemic circulation by the tight blood retinal barrier. Effective intraocular drug levels can be achieved with a much smaller amount of medication …

diabetic retinopathy
neovascularization
corrected visual acuity
retinopathy
adalimumab
  • 78 views
  • 07 Nov, 2020
  • 1 location
Subconjunctival Injection of Allogeneic Mesenchymal Stem Cells in Severe Ocular Chemical Burn

The objective of this pre-clinical study is to demonstrate the robustness of Bone Marrow derived Mesenchymal Stem Cells (BM-MSC) production, to treat patients with severe eye burns. For bone marrow donors who agree to participate, a 10 ml BM sample will be collected apart the 1 liter BM dedicated to …

  • 0 views
  • 15 Apr, 2021
  • 1 location