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Found 82 clinical trials
SAHaRA: A Randomized Controlled Trial

The SAHaRA trial will clarify the role of treating anemia with Red Blood Cell (RBC) transfusion in a unique and vulnerable patient population, and determine whether that impacts on functional outcomes and mortality. It will guide best practice standards and clarify the optimal RBC transfusion strategy in patients with aSAH.

  • 364 views
  • 02 Mar, 2022
  • 17 locations
SC IL-1Ra in SAH - Phase III Trial (SCIL) (SCIL)

This phase III trial will establish whether IL-1Ra, with sub-cutaneous (SC) administration twice daily for up to 21 days post aneurysmal subarachnoid haemorrhage (aSAH), improves clinical

withdrawn
  • 59 views
  • 04 Jun, 2022
  • 12 locations
International Subarachnoid Aneurysm Trial II

The purpose of this study is to compare the clinical outcome of surgical clipping and endovascular coiling for ruptured intracranial aneurysms not included in the original ISAT Study.

  • 40 views
  • 04 Aug, 2021
  • 6 locations
Auricular VNS Following Subarachnoid Hemorrhage

This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following spontaneous subarachnoid hemorrhage.

  • 1 views
  • 22 Dec, 2021
  • 1 location
Permanent Cerebral Oxymetry Monitoring for Early Diagnosis and Treatment of Delayed Vasospasm After Subarachnoid Hemorrhage (COMOVA)

measurement in order to detect vasospasm in patient with severe subarachnoid hemorrhage compare to standard monitoring tools.

vasospasm
transcranial doppler ultrasound
  • 0 views
  • 23 Apr, 2022
  • 1 location
Intraventricular Fibrinolysis Versus External Ventricular Drainage Alone in Aneurysmal Subarachnoid Hemorrhage: a Randomized Controlled Trial. (FIVHeMA)

Aneurysmal subarachnoid hemorrhage (SAH) is a devastating form of stroke, with delayed cerebral ischemia (DCI) as a major complication. There are several evidences, both in preclinical and in

hydrocephalus
cerebral infarction
alteplase
intracranial aneurysm
delayed cerebral ischaemia
  • 1 views
  • 22 Sep, 2022
  • 1 location
STORM: Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage (STORM)

aneurysmal subarachnoid hemorrhage (SAH) subjects in a neurocritical care setting. 25 patients will be enrolled, all treated with an active device. The primary efficacy outcomes are reduced aneurysm rupture

  • 0 views
  • 17 Sep, 2022
  • 1 location
Evaluate the Use of Glibenclamide on Acute aSAH

A randomized, open-labeled, blank-controlled and prospective trial meant to evaluate the use of glibenclamide on acute aneurysmatic subarachnoid hemorrhage. Patients will allocated randomly in

  • 0 views
  • 25 Mar, 2022
  • 1 location
Prediction of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage Using Dynamic 18F-FDG PET/CT (PREDISP)

A pilot trial for assessing early microvascular alterations after aneurysmal subarachnoid hemorrhage using dynamic 18F-FDG PET/CT. The primary endpoint will be the measure of early changes in

  • 0 views
  • 02 May, 2022
The Role of Meningeal Lymphatic Vessels in the Absorption of Chronic Subdural Hematoma and Its Injury Mechanism

such as Alzheimer's disease (AD), traumatic brain injury (TBI), and subarachnoid hemorrhage (SAH). This phenomenon suggests that mLVs play an important role in central nervous system diseases.

Accepts healthy volunteers
  • 0 views
  • 07 Jul, 2022
  • 1 location