Found 35 clinical trials
Internet-delivered Therapy for Alcohol Misuse: Factorial Trial of Assessment and Guidance
Internet-delivered cognitive behaviour therapy (ICBT) shows considerable promise as a convenient treatment for alcohol misuse. ICBT may differ in whether the user works alone (self-guided) or along with an individual who guides treatment (e.g., therapist/health educator). Guided ICBT involves completing online lessons over several weeks coupled with support from a …
- 27 views
- 23 Jan, 2021
- 1 location
Effects of Transcranial Direct Current Stimulation on Reward Learning in Subclinical Depression.
This project will test whether transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) can alter reward learning behaviour in subclinical depression. tDCS is a neuromodulation technique that uses weak electrical current to increase (anodal stimulation) or decrease (cathodal stimulation) the excitability of the stimulated brain region. A …
- 30 views
- 02 May, 2021
- 1 location
Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment
Recurrent fall/winter major depression (known as Seasonal Affective Disorder (SAD)) is a prevalent and disruptive disorder whose pathophysiological basis is unknown, but several hypotheses attribute a causal role to the circadian timing system. Bright white light exposure via the retina has been shown to reverse the symptoms of SAD. Recent …
- 262 views
- 07 Nov, 2020
- 1 location
Prevention of OUD: The HOME Project (Housing Opportunities Motivation and Engagement)
Homeless youth have a much higher rate of substance use than non-homeless peers with evidence suggesting that homeless youth have the highest rates of opioid use among youth subgroups in the country (Brands et al., 2005); heroin using homeless youth also appear to have the highest rates of IV drug …
- 0 views
- 08 Apr, 2021
- 1 location
Blended Care Versus Face-to-Face Therapy for Depression
Depression is a severe mental disorder that affects 5-7% of Belgians each year. Unfortunately, many individuals with depression do not seek professional help, and if they do seek professional help, waiting lists for psychotherapy are typically very long. To help resolve this problem, this study aims to investigate whether blended …
- 0 views
- 24 Jan, 2021
- 5 locations
Adjunctive Vortioxetine in Schizophrenia
with a research diagnosis of schizophrenia determined with the Structured Clinical Interview for DSM (SCID). Patient randomization will be stratified by illness duration (i.e., </=5 years and >5
- 70 views
- 22 Feb, 2021
- 3 locations
Conquering Feared Foods Study
feared food. The investigators are conducting a pilot clinical measurement study. Participants will be screened for eating disorder symptoms via a structured clinical interview. Participants with or
- 68 views
- 04 Apr, 2021
- 1 location
The Use Of L-Methylfolate As A Treatment For Depression
to moderate MDD based on the Structured Clinical Interview for DSM-IV (SCID) that have a Hamilton Depression Rating Scale-24 (HDRS-24) score between 8-24. The investigators will collect genotype data
- 166 views
- 14 Jun, 2021
- 1 location
Psychometric Properties of the International Trauma Interview (ITI) for ICD-11 PTSD and CPTSD
The aim of the project is to evaluate the psychometric properties (e.g. validity, reliability) of the International Trauma Interview (ITI) - German version. The ITI is a structured clinical
- 2 views
- 24 Jan, 2021
- 2 locations
Testing the Use of Interoceptive Exposure to Reduce Barriers to Psychotherapy
-intervention assessment at UMC (structured clinical interview, self-report measures, and a treatment-engagement analogue exercise). Half of the participants will be randomized into either supportive
- 161 views
- 07 Nov, 2020
- 1 location