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Found 67 clinical trials
Renal Tumors Classification, Biology, and Banking Study

This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.

renal neoplasm
papillary renal cell carcinoma
  • 20 Sep, 2022
  • 96 locations
Integrated Cancer Repository for Cancer Research (iCaRe2)

The iCaRe2 is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant …

primary cancer
Accepts healthy volunteers
early diagnosis
early detection
  • 13 Mar, 2022
  • 61 locations
DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

Background Pleuropulmonary blastoma (PPB) is a rare fast-growing lung tumor that is associated with other, rare tumor types. Most cases of PPB appear in children younger than 6 years of age. Recently, it has been shown that this condition can be inherited (e.g., mutation of the DICER1 gene). Researchers are …

Accepts healthy volunteers
  • 22 Sep, 2022
  • 2 locations
Natural History and Biospecimen Acquisition Study for Children and Adults With Rare Solid Tumors

Background Approximately 150 cases of cancer per one million per year are considered rare cancers. While all tumors originate from genetic changes, a small percentage of these tumors are familial. Researchers want to study these changes in biological samples from people with rare tumors in order to learn more about …

solid tumor
Accepts healthy volunteers
cns tumor
  • 16 Sep, 2022
  • 4 locations
Observational Study on Endometrial Stromal Tumors (EST)

Observational, retrospective and prospective study on Endometrial Stromal Tumor (EST)

stromal tumor
cancer chemotherapy
  • 24 Feb, 2022
  • 1 location
International Ovarian & Testicular Stromal Tumor Registry

Rare tumors are understudied, yet have the potential to shed light on vast areas of cancer research. Ovarian sex cord-stromal tumors, rare tumors of childhood and young adulthood, have recently

  • 02 Jun, 2021
  • 1 location
Oncogenetic Panel and Integrated Clinical Data Registry Study for Wild Type Gastrointestinal Stromal Tumor Patients (GIST)

treatment. In addition, the investigators want to correlate the clinical outcome with the genetic aberrations of the cancer patients in Taiwan. Gastrointestinal stromal tumor (GIST) is a rare cancer

  • 27 Jun, 2022
  • 12 locations
Prospective Study of Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

Objective To follow people with GISTs and collect tumor tissue so that it can be studied in the lab. Eligibility People age 6 and older who have a GIST. Design Participants will be screened with a review of their medical records and samples. Participants will enroll in 1 other NIH …

ct scan
  • 19 Sep, 2022
  • 1 location
Ripretinib Combined With Surgery in Advanced GIST That Have Failed Imatinib Therapy: A Multicenter,Observational Study

The objective of this observational study is to explore the efficacy and safety of ripretinib treatment combined with surgery in advanced gastrointestinal stromal tumors(GIST) after failure of

  • 14 May, 2022
  • 1 location
GIST: Assessment of Tumor Mutations and TKI Plasma Exposure

Gastrointestinal stromal tumors (GISTs) belong to the sarcoma group and are characterized by oncogenic mutations in the c-KIT, PDGFRA, BRAF and NF-1 genes that drive tumor growth. Since tyrosine

  • 29 May, 2022
  • 1 location