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Found 67 clinical trials
A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

This study will assess the safety, efficacy, and pharmacokinetics of THE-630 in participants with advanced gastrointestinal stromal tumors (GIST).

bone marrow procedure
primary cancer
immunostimulants
cancer
neuropathy
  • 0 views
  • 28 Jul, 2022
  • 6 locations
TC or BEP in Treating Patients With Ovarian Malignant Sex Cord-Stromal Tumors (SCST-01)

newly diagnosed ovarian malignant sex cord-stromal tumor patients after surgery.

etoposide
paclitaxel
residual tumor
carboplatin/paclitaxel
carboplatin
  • 38 views
  • 12 Feb, 2022
  • 1 location
Safety of Laparoscopic Resection for Gastrointestinal Stromal Tumor on Unfavorable Anatomic Site of Stomach

The aim of this trial is to evaluate the safety of laparoscopic resection for GIST whose diameter is ≥2cm and ≤5cm at unfavorable anatomic sites of stomach.

  • 0 views
  • 21 Mar, 2022
  • 1 location
A Study of Avelumab In Combination With Axitinib in Patients With Unresectable/Metastatic Gastrointestinal Stromal Tumor After Failure of Standard Therapy (AXAGIST)

To assess anti-tumor activity of avelumab in combination with axitinib in patients with unresectable/metastatic GIST after progression on second or third line treatment (after failure on at least of imatinib and sunitinib) in terms of progression-free survival (PFS)

neutrophil count
imatinib
anticoagulants
platelet count
metastasis
  • 0 views
  • 25 Feb, 2022
  • 1 location
Efficacy and Safety of Famitinib Versus Sunitinib in the Treatment of Advanced Gastrointestinal Stromal Tumour Patients After Failure of Imatinib

The study is being conducted to evaluate the efficacy and safety of famitinib in the treatment of advanced gastrointestinal stromal tumour patients after failure of imatinib compared to

  • 2 views
  • 27 Jan, 2021
  • 1 location
Ripretinib Used for Resectable Metastatic GIST After Failure of Imatinib Therapy

To explore the efficacy and safety of preoperative treatment of potentially resectable locally advanced or recurrent metastatic gastrointestinal stromal tumor (GIST) after failure of treatment

  • 0 views
  • 01 Dec, 2021
  • 1 location
Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST (REGISTRI)

Evaluate the treatment with regorafenib in patients with metastatic and/or unresectable KIT/PDGFR wild type GIST in the first line setting.

neutrophil count
warfarin
platelet count
thromboplastin
KIT
  • 0 views
  • 26 Jan, 2022
  • 15 locations
Endoscopic Ultrasound Radiofrequency Ablation for GISTs

Nowadays, for the selection of the treatment for gastrointestinal stromal tumors (GISTs), tumor size, prognosis, resectability and stage should be considered. Due to mutations in KIT and

  • 0 views
  • 28 Jul, 2022
  • 1 location
ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST

The purpose of this research is to test if mutations (changes in DNA) in exons (segment of DNA or RNA containing information that has the instructions for making proteins) in the KIT gene can be used to predict the body's response to standard of care treatment.

  • 0 views
  • 11 Aug, 2022
  • 1 location
A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101)

stromal tumors (GIST) who are judged to be refractory to imatinib, estimate the recommended dose, evaluate safety and pharmacokinetics, and observe the antitumor effect. Expansion part consists of 3 arms

  • 0 views
  • 11 Aug, 2022
  • 1 location