Found 71 clinical trials
Immunological Mechanisms Underlying Neuroprotection from Exercise in Alzheimer’s disease
This study is looking for healthy people over the age of 60. There is no treatment or experiment being tested. The study is interested in the relationship between genetics, physical activity, and the risk of developing Alzheimer’s.
- 0 views
- 25 Feb, 2022
- 1 location
Determining correlation of altered heart rate regulation and reduced glymphatic clearance in Alzheimer disease
This study is looking for people who have early Alzheimer’s. The study is interested in the relationship between heart health and brain health in Alzheimer’s.
- 0 views
- 24 Mar, 2022
- 1 location
Effects of Exercise & Tart Cherry Ingestion on Heat Acclimation and Gut Microbiome
The purpose of this study is to determine whether tart cherry supplementation effects thermotolerance and heat acclimation in human subjects exposed to exercise/heat stress. Specific Aim I. To determine if tart cherry in combination with repeated bouts of thermally stressful exercise will impact the gut microbiome & inflammation measured via …
- 0 views
- 16 Oct, 2022
MechSens - Dose-response Relationship of in Vivo Ambulatory Load and Mechanosensitive Cartilage Biomarkers (MechSens)
This study is to investigate the effects of age, tissue status and the presence of inflammation on the in vivo dose-response relationship of ambulatory load and mechanosensitive blood markers of articular cartilage.
- 5 views
- 15 Mar, 2022
- 1 location
Metabolic, Functional and Nutritional Responses to Weight Cycling in Athletes: The WAVE Study (WAVE)
Many elite athletes are submitted to frequent rapid weight loss periods to meet their competition weight category and then experience weight cycling (lowing and gaining weight regularly). This weight cycling induce severe temporary energetic and metabolic changes and when repeated over time can lead to permanent metabolic adaptations that might …
- 0 views
- 14 Jun, 2022
- 1 location
Benefits of Ketogenic Diet in Patients With Heart Failure With Preserved Ejection Fraction: A Pilot Study
This study is being done to evaluate the effects of a low carbohydrate ketogenic diet on exercise tolerance in patients with Heart Failure with Preserved Ejection Fraction (HFpEF), also known as Diastolic Heart Failure (DHF).
- 36 views
- 23 Oct, 2022
- 1 location
Clinical Pharmacology and Target Validation of A Bioactive Dietary Polyphenol Preparation (BDPP) For Stress-Related Disorders
This study will characterize the clinical pharmacology of a select bioactive polyphenol-rich preparation (Bioactive Dietary Polyphenol Preparation, BDPP) comprised of a select Concord grape juice (CGJ), a select grape seed polyphenol extract (GSPE) and trans-resveratrol (RSV).
- 0 views
- 28 Oct, 2022
- 1 location
Human Cerebral Blood Flow Regulation (Gas Challenge)
This study tests basic differences in how men and women control brain (cerebral) blood flow (CBF), at rest and under stress. The stress is low oxygen or high carbon dioxide. The investigators hypothesize that sex differences per se, plus sex hormone differences, drive different signals in blood vessels that change …
- 4 views
- 04 Oct, 2022
- 1 location
Exercise Testing in Diseases and Health
Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population. CPET provides a full assessment of the physiologic responses of the pulmonary, cardiovascular, muscular, and cellular oxidative systems to exercise. The test progression include a incremental stepwise (on treadmill) or …
- 0 views
- 13 Apr, 2022
- 1 location
Assessment of Patients With suspeCted Coronary Artery Disease by Coronary calciUm fiRst strATegy vErsus Usual Care Approach. (ACCURATE)
in symptomatic patients presenting for evaluation of possible coronary artery disease (CAD) prior to the cardiac PET stress test, can be used as a gatekeeper for progression to the expensive rubidium
- 0 views
- 04 Oct, 2022
- 1 location