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Found 553 clinical trials
MRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients

Overall Research Strategy of this protocol is to refine and validate noninvasive CMR imaging sequences with invasive hemodynamic and pathology results to create a comprehensive, noninvasive, radiation-reduced regimen for pediatric cardiomyopathy and cardiac transplant assessment. We were the first to perform MR-guided cardiac catheterization in US children, and have accumulated …

cardiovascular catheterization
right heart catheterization
  • 12 Aug, 2022
  • 1 location
Can Gait Analysis and Ultrasound Detect a Change in Calf Musculature in Children With Cerebral Palsy?

ORLAU is a clinical department of the Robert Jones and Agnes Hunt Orthopaedic Hospital. We treat patients with a wide range of movement disorders affecting their walking or arm function. One of the most common gait issues we see is toe-walking, this is most prevalent in those patients with cerebral …

gait analysis
botulinum toxin
  • 22 Mar, 2022
  • 1 location
Pulse Wave Parameters in the Assessment of Systolic Function of the Left Ventricle.

This is a prospective, single-center, non-randomized, observational study. The aim of this study is to determine the potential of a single-lead electrocardiogram monitor CardioQvark with photoplethysmography function use to evaluate systolic function of the left ventricle. The study is conducted in the clinic of I.M. Sechenov First Moscow State Medical …

left bundle branch block
  • 11 May, 2022
  • 1 location
Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study

NIMBLE is a prospective study for blood biomarker study of lung nodules alongside analysing data which has been collected routinely as part of patient care. The primary aim of NIMBLE is to assess whether artificial intelligence and machine learning based radiomics approaches can be used to distinguish between benign disease …

lung cancer
lung carcinoma
  • 15 Jul, 2022
  • 1 location
Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy

Recently chimeric antigen receptor (CAR) T-cell therapy, a new class of chemo therapy, has gained regulatory approval for the treatment of diseases such as B-cell lymphoma. Known side effects include cytokine release syndrome, which has been described to lead to myocarditis, but larger studies exploring this relationship are currently lacking. …

b-cell lymphoma
cardiac mri
chemotherapy regimen
  • 06 Jul, 2022
  • 1 location
Microbiome in Obsessive-compulsive Disorder (MIO)

Background: Humans live in symbiosis with microbes and their implication for health and disease is evident. The importance of microbiome-gut-brain axis in psychiatric disorders is an area of increasing research interest. OCD is a promising target for microbiome research as Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)/ Pediatric autoimmune neuropsychiatric disorders associated …

Accepts healthy volunteers
psychiatric disorder
behavior therapy
streptococcal infection
pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections
  • 29 Apr, 2022
  • 1 location
Cardiac MRI and Cardiac Allograft Rejection

In this a prospective, blinded, collaboration study between pediatric and adult transplant departments. Cardiac MRI data on patient with heart transplantations will be collected during years 2020-2022. Based on sample size calculations, the data has enough power to answer the question, whether MRI can be used as a noninvasive diagnostic …

  • 02 Mar, 2022
  • 1 location
Endobronchial Valves Positioning Effects On Diaphragm Function In Patients With Lung Hyperinflation (EVELHYN)

This prospective study aims at evaluating diaphragmatic function before and after endobronchial valves positioning in a COPD patients with lung hyperinflation.

  • 06 Apr, 2022
  • 1 location
Clinical Functional Immunological and Genetic Factors on the Severity of the Course of Coronavirus Infection

The purpose of the program. To determine the clinical, functional, immunological, and genetic factors affecting the severity of the course of acute coronavirus infection COVID-19 and PostCovid syndrome, in order to develop management tactics for such patients to reduce the risk of complications and disability.

  • 11 Aug, 2021
  • 1 location
Efficacy of a Multiplex BangasureTM RT-PCR Kit for the Detection of COVID-19 (COVID-19)

The outbreak of the severe acute respiratory syndrome (SARS) corona virus (CoV)-2 continues to increase globally. To control the coronavirus disease 2019 (COVID-19) transmission, diagnose is very important step which would help in the process of quarantine, isolation of the infected person and also in contact tracing. Among the various …

  • 13 Jun, 2022
  • 1 location