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Found 565 clinical trials
Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

with atezolizumab or other immune checkpoint inhibitors in HLA-A*02+ patients with recurrent, locally advanced or metastatic human papillomavirus strain 16 positive (HPV16+) solid tumors. The study

measurable disease
solid tumour
  • 26 May, 2022
  • 10 locations
OH2 Oncolytic Viral Therapy in Non-Muscle-Invasive Bladder Cancer

> OH2 is an oncolytic virus developed upon genetic modifications of the herpes simplex virus type 2 strain HG52, allowing the virus to selectively replicate in tumors. Meanwhile, the delivery of the

  • 22 Jul, 2022
  • 1 location
Saltikva for Metastatic Pancreatic Cancer

Objectives: Assess the efficacy of multiple dose oral administration of Saltikva, an attenuated strain of Salmonella Typhimurium expressing IL-2, in patients with metastatic pancreatic cancer on

  • 13 May, 2022
  • 1 location
Probiotic Modulation of Oral Microbiota (PROROBIOTICS)

consensus inflammatory status of the whole mouth with potentially significant clinical relevance. Strain K12 of Streptococcus salivarius is available internationally as a food supplement, notably

Accepts healthy volunteers
  • 09 Apr, 2022
Clinical Trial of Probiotic Supplementation in Psoriasis Vulgaris

infection, obesity, smoking, and drugs. The provision of probiotic Lactobacillus plantarum IS-10506, an Indonesian original probiotic strain, is expected to be an effective, safe, and affordable

Accepts healthy volunteers
  • 10 Mar, 2022
  • 1 location
Feasibility Study of Microbial Ecosystem Therapeutics (MET-4) to Evaluate Effects of Fecal Microbiome in Patients on ImmunOtherapy (MET4-IO)

This study is designed to assess the safety, tolerability and engraftment (cumulative relative abundance) of MET-4 strains when given in combination with immune checkpoint inhibitors (ICIs

  • 01 May, 2022
  • 1 location
Clinical Evaluation of Vertical Inter-implant Papilla Height in Platform Matched Implants in Comparison to Morse Connection Abutments

might help reducing marginal bone remodeling during biological width formation. Moreover, the literature indicates that the peri-implant bone strain vary significantly with the type of implant-abutment

  • 26 Sep, 2021
  • 1 location
Norovirus Challenge Study (G1-1 Challenge)

appearance and number to active vaccine tablets Approximately 28 days post-vaccination, subjects will be admitted to an isolation ward and challenged with the NV GI.1 Norwalk challenge strain

Accepts healthy volunteers
  • 15 May, 2022
  • 1 location
Chronic Ankle Instability, Surgical Repair: Open Versus Closed (CAISR)

Rationale: Lateral ankle ligament injuries may be a result of ankle sprains. In 10-30% of patients with lateral ankle ligament injuries, chronic lateral ankle instability may be present. If

  • 25 Feb, 2022
  • 1 location
The Effects of Respiratory Training on Voice

voice clinics. Perceptually the voice sounds hoarse and strained, with reduced loudness and pitch range, and people with MTD find speaking very effortful and fatiguing. The physiological abnormalities

  • 05 Jun, 2021
  • 1 location