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Found 433 clinical trials
Featured trial
Study to Assess the Efficacy Safety and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)  

Primary Objective: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former …

  • 27 Sep, 2022
  • 58 locations
Featured trial
Ankylosing Spondylitis Study

and stiffness of ankylosing spondylitis (AS) symptoms despite treatment, you may want to consider participating in a research study of an oral investigational medication for AS.  

  • 23 Nov, 2020
  • 1 location
Featured trial
Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

) taken Body mass index measured Cardio-Ankle Vascular Index test. The stiffness of the participant s arteries will be measured by reading blood pressure in the arms and legs and

fish oil
fatty acids
  • 23 Nov, 2020
  • 1 location
Featured trial
Knee Joint Function in Adults 40-75

Pain and stiffness in the knees is a common problem, regularly treated with a combination of exercise, surgery, and/or medicinal pain relievers. Early intervention and maintained treatment

knee pain
  • 18 Jun, 2021
  • 1 location
Featured trial
When your joints ache...everyday life becomes a chore.

When your joints ache...everyday life becomes a chore.

  • 08 Nov, 2020
  • 2 locations
A Multicenter, Double-blind, Placebo-controlled, Randomized, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of JNJ-67484703 in Participants With Active Rheumatoid Arthritis

The purpose of this study is to evaluate safety and tolerability of JNJ-67484703 administrations in participants with active rheumatoid arthritis (RA).

biologic disease-modifying antirheumatic drug
body mass index
  • 19 Aug, 2022
  • 9 locations
Anatomical Radiological and Biomechanical Examination of Athletic Groin Pain Patients and Physical Therapy Intervention

Athletic groin pain (AGP) is a chronic condition common in multi-directional sports (Walden et al. 2007, Robinson et al. 2004, Murphy et al. 2012). It is a complex injury with a challenging diagnosis. Dramatic differences in the anatomical diagnoses of AGP cohorts exist in the literature (Renstrom et al. 1980, …

  • 21 Jan, 2021
  • 1 location
Peripheral Modulation of Muscle Stiffness and Spasticity

stiffness. The investigators will recruit 50 subjects, 25 males and 25 females, who will be randomized to receive either hyaluronidase plus saline (treatment arm, n=25) or normal saline (control arm, n=25

  • 24 Mar, 2022
  • 1 location
Can Vitamin C Reduce the Risk of Postoperative Shoulder Stiffness? A Mono-center, Double-blinded, Randomized and Placebo-controlled Study (VitC)

Postoperative shoulder stiffness is a common complication after shoulder surgery (incidence 10-15%). The symptoms consist primarily in a painful impairment of the mobility of the glenohumeral

  • 18 Sep, 2022
  • 1 location
Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool? (ELASTOCARDIO2)

The new approach propose in this protocol is based on ultrafast ultrasound and remote palpation of tissue by ultrasonic radiation pressure. Ultrafast ultrasound of biological tissues is based on an innovative ultrasound imaging approach that can image very fast soft tissue events at a rate of several thousands of frames …

  • 08 Apr, 2022
  • 1 location