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Found 33 clinical trials
Idiopathic Granulomatous Mastitis Combination Therapy (IGM-COMBO)

After breast cancer, diopathic Granulomatous Mastitis (IGM) is among the breast diseases that bother patients and clinicians the most. Countries with a coast to the Mediterranean, especially our country, are the most common geography of this disease. For this reason, a significant part of the important scientific publications about IGM …

  • 14 May, 2022
Tocilizumab in Active Moderate-severe Graves' Orbitopathy

To treat patientis with active moderate-severe GO with the anti-IL6 receptor monoclonal antibody tocilizubam with the purpose of assesing the efficacy of therapy on active GO and on the proportion of patiens with inactivation and reactivation of disease (Primary Objective) Effect of therapy on disease progression, improvement of QoL, the …

  • 16 May, 2021
  • 4 locations
DEXTENZA Compared to Topical Steroid Therapy Prior to Cataract Surgery in Patients Who Receive Premium Intraocular Lenses

The investigators seek to assess the effect of pre-operative and continued post-operative corticosteroid use on pain, patient preference, visual outcomes, and change in objective quantifiable biological parameters in patients undergoing bilateral cataract surgery with premium intraocular lens implantation with or without baseline ocular surface disease. Patient's first eye scheduled for …

  • 26 Mar, 2021
  • 1 location
High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors

This phase I/II trial studies the side effect and best dose of steroid therapy (prednisone or methylprednisolone) in improving symptoms of late radiation-associated lower cranial neuropathy in

neck cancer
cranial neuropathy
head and neck cancer
  • 27 May, 2022
  • 1 location
Intravenous Methylprednisolone Versus Oral Prednisolone for Infantile Spasms (MPIV)

associated with prolonged oral steroid therapy and maintain long-term efficacy.However, there are no studies comparing iv methylprednisolone pulse therapy with high dose oral prednisolone..

methylprednisolone oral
oral prednisolone
epileptic spasms
  • 18 Feb, 2022
  • 1 location
Dexamethasone Solution and Dexamethasone in Mucolox™

Topical steroid therapy is considered the first line of treatment for Oral Inflammatory Ulcerative Diseases with current treatment regimens requiring multiple application or rinses daily. Using

Accepts healthy volunteers
  • 08 Apr, 2022
  • 1 location
Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

disease that does not respond to steroid therapy (steroid-refractory). Ruxolitinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. cb-MSCs are a type of tissue

cell transplantation
graft versus host disease
acute graft versus host disease
donor lymphocyte infusion
  • 21 Mar, 2022
  • 1 location
RItuximab From the FIRst Episode of Idiopathic Nephrotic Syndrome

oral steroid therapy at the dose of 1mg/kg/day (max 80 mg/day) for a minimum of 4 weeks and a maximum of 16 weeks (as tolerated) constitutes the first line treatment of adults with MCNS. Despite of

  • 19 Jul, 2021
  • 1 location
Prophylactic Implantation of Biologic Mesh in Peritonitis

, previous abdominal incisions, steroid therapy). Data about the use of biological prosthesis in infected fields are scarce and derive principally from case reports and case series. However, indications

  • 28 Jan, 2021
  • 1 location
Intraocular Pressure in Children With Acute Lymphoblastic Leukemia (ALL) Treated With High Dose Steroids

Childhood ALL patients are treated with high dose steroids. The study will follow the intraocular pressure of children treated in according to an AIEOP-BFM protocol, during the induction phase that will be compared to the pressure before treatment. Potential risk factors for developing elevated intraocular pressure will be estimated.

  • 27 Oct, 2021
  • 1 location