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Found 27 clinical trials
Woodsmoke Particulate + Prednisone (Smokisone)

oral steroid treatment can reduce the airway inflammation caused by the inhaled WSP. The exposure will be 500 µg/m³ of WSP for 2 hours, with intermittent exercise on a bicycle and rest. The wood is

Accepts healthy volunteers
  • 0 views
  • 21 Mar, 2022
  • 1 location
High Dose Steroids in Children With Stroke (PASTA)

) combined with high dose steroids. The second group will be treated with standard of care (including aspirin) but without steroid treatment. The objective is to investigate if children treated with a

  • 0 views
  • 12 Mar, 2022
  • 3 locations
Do We Need to Taper Down Steroid Therapy for Bell's Palsy

levels of noise and disturbed sense of taste on the same side. It affects men and women more or less equally. There is a consensus in the literature regarding the importance of steroid treatment

  • 1 views
  • 24 Jan, 2021
  • 1 location
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial (ADVISE)

Non-infectious intermediate, posterior, and panuveitides are chronic, potentially-blinding diseases. Vision-threatening cases require long-term therapy with oral corticosteroids and immunosuppression. Based upon preliminary data, adalimumab, a fully-human, anti-TNFmonoclonal antibody, now US FDA-approved for uveitis treatment, may be a superior corticosteroid-sparing agent than conventional immunosuppressive drugs. The ADVISE Trial is multicenter randomized, …

panuveitis
methotrexate
tumor necrosis factor
tacrolimus
adalimumab
  • 124 views
  • 18 Feb, 2022
  • 18 locations
Evaluate the Efficacy and Safety of FB825 in Adult With Allergic Asthma

This is a randomized, placebo-controlled and double-blind study to evaluate the efficacy and safety of FB825 in adult patients with moderate-to-severe allergic asthma.

  • 0 views
  • 21 Apr, 2022
  • 4 locations
KIDS-STEP_Betamethasone Therapy in Hospitalised Children With CAP (KIDS-STEP)

The purpose of this study is to concurrently evaluate whether adjunct treatment with corticosteroids in children hospitalized with CAP is more effective in terms of the proportion of children reaching clinical stability and whether such adjunct treatment is no worse in terms of CAP relapse.

corticosteroids
  • 3 views
  • 16 Feb, 2022
  • 8 locations
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest (STEROHCA)

Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death. This study will investigate the anti-inflammatory and neuroprotective effect of early treatment with the glucocorticoid methylprednisolone measured by interleukin-6 and …

interleukin-6
inflammatory response
  • 0 views
  • 10 Mar, 2022
  • 2 locations
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing (INSTAR)

The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection. The secondary objectives are to determine duration and severity of each acute episode with acute expiratory breathing difficulty, the number of episodes …

corticosteroids
wheezing
corticosteroid therapy
steroid therapy
  • 34 views
  • 12 Feb, 2022
  • 8 locations
Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease

This is a single arm phase 2 trial which includes patients with high risk acute GVHD defined as Ann Arbor score 2 or 3. The purpose of the study is to improve the outcome of these patients in terms of response to treatment and treatment related mortality. All patients will …

  • 0 views
  • 10 Oct, 2021
  • 3 locations
Melanoma Metastasized to the Brain and Steroids (MEMBRAINS)

patients with brain metastases and in need of steroid treatment. Patients will be treated in four arms depending on steroid dose level at inclusion (> 10 < 25 mg prednisolone or > 25 mg

brain metastases
BRAF
metastasis
trametinib
nivolumab
  • 89 views
  • 04 Mar, 2022
  • 1 location