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Found 155 clinical trials
Prostate Cancer With OligometaSTatic Relapse: Combining Stereotactic Ablative Radiotherapy and Durvalumab (MEDI4736) (POSTCARD)

SBRT targeting oligometastatic lesions. In this randomized 2:1 phase II trial of Stereotactic Body Radiation Therapy with or without durvalumab in oligometastatic hormone sensitive prostate cancer

bone scan
platelet count
neutrophil count
stereotactic body radiation therapy
metastasis
  • 16 views
  • 08 Feb, 2022
  • 1 location
Microwave Ablation of Primary and Secondary Lung Malignancies

alternatives to surgery so that local control of unresectable tumors can be achieved. Stereotactic body radiation therapy (SBRT) is currently an alternative therapy for these patients with 3-year

  • 0 views
  • 26 Jan, 2021
  • 1 location
Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc) (Stereosarc)

body radiation therapy (SBRT) is associated with excellent tolerance. Surgery may be offered in selected metastatic cases. Alternatively and increasingly, SBRT yields high control rates at treated

liposarcoma
ipilimumab
neutrophil count
tumor cells
leiomyosarcoma
  • 0 views
  • 10 Aug, 2022
  • 1 location
Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab

The purpose of this research study is to find out what effects (good and bad) Pembrolizumab and radiosurgery have on participants with high-grade epidural disease of the spine.

primary cancer
  • 0 views
  • 30 May, 2022
  • 1 location
COmbination of Radiotherapy With Anti-PD-1 Antibody for unREseCtable Biliary Tract Cancer (CORRECT)

The study is a single-arm, phase II trial. The purpose is to investigate both the efficacy and safety of radiotherapy combined with anti-PD-1 antibody in unresectable biliary tract cancer patients.

renal function
gemcitabine
unresectable intrahepatic cholangiocarcinoma
kidney function tests
measurable disease
  • 35 views
  • 16 Jun, 2022
  • 1 location
Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer (PLATON)

The purpose of this study is to compare the effects of ablative therapy (radiation or surgery) to all sites of disease combined with standard treatments on prostate cancer, compared to the standard or usual treatments used to treat this disease.

bone scan
adenocarcinoma
adenocarcinoma of prostate
metastasis
cfdna
  • 71 views
  • 22 Mar, 2022
  • 14 locations
Thoracic Re-irradiation For Locoregionally Recurrent Non-small Cell Lung Cancer

This prospective phase II study is to assess the efficacy and safety of thoracic re-irradiation for locoregionally recurrent non-small cell lung cancer using hypofractionated technique.

  • 1 views
  • 27 Feb, 2022
  • 1 location
Liver Directed RT + Chemo-immunotherapy for ES-SCLC

The purpose of this study is to evaluate whether radiation treatment directed at liver metastases can be safely added to standard of care treatment for extensive stage small cell lung cancer (ES-SCLC). The current standard treatment for people who have ES-SCLC is chemotherapy including drugs called carboplatin and etoposide, that …

aptt
carboplatin
neutrophil count
international normalized ratio
etoposide
  • 0 views
  • 01 May, 2022
Efficacy and Safety of Involving Field Radiotherapy in the Oligo-lesions(Metastasis/Recurrent/Refractory) of Ovarian Cancer

In this study, The researchers sought to explore the efficacy and safety of involving field radiotherapy in the oligo-metastatic/recurrent/refractory ovarian cancer patients among different groups which include drug therapy alone, radiotherapy alone, and drug therapy plus radiotherapy by inviting clinical multi-center participation.

peritoneal cancer
fallopian tube
metastasis
cancer of the ovary
cancer chemotherapy
  • 0 views
  • 07 Oct, 2021
  • 1 location
SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer (SHARP)

Random assignment between SBRT and conventionally fractionated boost following HDR brachytherapy for prostate cancer.

  • 0 views
  • 10 May, 2022
  • 1 location