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Found 153 clinical trials
Durvalumab vs Placebo With Stereotactic Body Radiation Therapy in Early Stage Unresected Non-small Cell Lung Cancer (NSCLC) Patients / Osimertinib Following SBRT in Patients With Early Stage Unresected NSCLC Harboring an EGFR Mutation (PACIFIC-4)

This is a Phase III, randomized, placebo-controlled, double-blind, multi-center study assessing the efficacy and safety of durvalumab with SoC SBRT versus placebo with SoC SBRT in patients with unresected clinical Stage I/II lymph node-negative (T1 to T3N0M0) NSCLC. An additional cohort will assess Osimertinib following SBRT in patients with early …

durvalumab
stereotactic body radiation therapy
lung carcinoma
osimertinib
EGFR
  • 208 views
  • 14 Jul, 2022
  • 162 locations
Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma

This phase II trial studies how well stereotactic body radiation therapy and aflibercept work in treating patients with uveal melanoma. Stereotactic body radiation therapy is a specialized

  • 0 views
  • 22 Aug, 2021
  • 1 location
Pancreatic Adenocarcinoma Neoadjuvant Combination Chemotherapy and Stereotactic Body Radiation Therapy Before Surgery

This is a single-arm, single-center feasibility trial of patients with borderline resectable pancreatic adenocarcinoma receiving radiation therapy with Stereotactic body radiation therapy (SBRT

  • 0 views
  • 18 Sep, 2021
  • 1 location
18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

> Eligibility People ages 18 and older with newly diagnosed prostate cancer who have no evidence of distant metastatic disease and plan to get stereotactic body radiation

  • 0 views
  • 27 Jul, 2022
  • 1 location
Clinical Trial Comparing Dose-intensified SBRT With Conventional Radiation Therapy for Spinal Metastases (DOSIS RCT)

This study will compare pain (primary end-point) and local metastatic tumor control (secondary end-point) after dose-intensified image-guided fractionated stereotactic body radiation therapy

  • 0 views
  • 23 Feb, 2022
SBRT Followed by Neoadjuvant Immunochemotherapy in Resectable Stage IB to III Non-small Cell Lung Cancer (SACTION01)

The purpose of this study is to find out the effectiveness stereotactic body radiation therapy (SBRT) followed by two cycles of Tislelizumab (PD-1 inhibitor) with chemotherapy as treatment for

stereotactic body radiation therapy
neutrophil count
lung carcinoma
cancer chemotherapy
EGFR
  • 0 views
  • 30 May, 2022
  • 1 location
SBRT for Oligoprogressive NSCLC After Treatment With PD-1 Immune Checkpoint Inhibitors

Despite the impressive response rate to PD-1 immune checkpoint inhibitors, resistance inevitably develops in most patients. Stereotactic body radiation therapy (SBRT) plays a growing role in the

  • 0 views
  • 04 Mar, 2021
  • 1 location
Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma

The specific aims of this study are: To determine the safety and feasibility of treating patients with a combination of MRI guided stereotactic body radiation therapy and microwave

metastasis
carcinoma
primary tumor
  • 6 views
  • 27 Jan, 2022
  • 1 location
SBRT for Oligoprogressive NSCLC After First Line Treatment With Immune Checkpoint Inhibitors

immunotherapy, and more than 1/2 patients are oligoprogressive. Stereotactic body radiation therapy (SBRT) plays a growing role in the management of oligometastatic disease. This study aims to evaluate the

  • 0 views
  • 05 Jun, 2022
  • 1 location
Lymphocyte Depletion and Change in Lymphocyte Functionality

NSCLC and will be receiving a type of radiation therapy called stereotactic body radiation therapy (SBRT) where high doses of radiation will be delivered to the tumor, while minimizing damage to healthy

  • 0 views
  • 28 Feb, 2022
  • 1 location