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Found 71 clinical trials
A Scalable Psychological Intervention to Reduce Psychological Distress Among Healthcare Workers

) and conditionally PM+ (step 2) if participants still meet criteria for psychological distress (Kessler Psychological Distress scale (K10) >15.9) 1 month after having received DWM. Main

anxiety
behavior therapy
depressed mood
  • 0 views
  • 10 Dec, 2021
  • 2 locations
Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit (IMAGE)

). Patients with concerning results will be placed in an ED Observation Unit for (step 2) multidisciplinary geriatric assessment. In Aim 1 we will use the Consolidated Framework for Implementation Research

  • 0 views
  • 16 May, 2022
  • 1 location
Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment Interruption

The purpose of this study is to evaluate the safety, tolerability, and efficacy of N-803, an IL-15 superagonist, with or without combination broadly neutralizing antibodies (bNAbs), to induce HIV-1 control during analytic treatment interruption (ATI).

lamivudine
HIV Vaccine
hiv-1 rna measurement
dolutegravir
  • 0 views
  • 29 Apr, 2022
  • 7 locations
Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1

The purpose of this study is to assess the safety, tolerability, pharmacokinetics, and antiviral activity of long-acting cabotegravir (CAB LA) plus the broadly neutralizing monoclonal antibody,VRC-HIVMAB075-00-AB (VRC07-523LS), in adults living with HIV-1 with suppressed plasma viremia.

reverse transcriptase inhibitor
antibody test
viremia
hepatitis
hiv-1 rna measurement
  • 126 views
  • 12 May, 2022
  • 22 locations
Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection (PURGE-C)

The purpose of this study is to assess the efficacy of a fixed dose combination (FDC) of glecaprevir/pibrentasvir (G/P) given for 4 weeks in acute hepatitis C (HCV)-infected participants, with or without HIV-1 coinfection.

ribavirin
hepatitis
glecaprevir
HIV Vaccine
pibrentasvir
  • 16 views
  • 24 Mar, 2022
  • 13 locations
Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia

Low doses of radiation in the form of chest x-rays has been in the past to treat people with pneumonia. This treatment was thought to reduce inflammation and was found to be effective without side effects. However, it was an expensive treatment and was eventually replaced with less expensive treatment …

cancer
SARS
dyspnea
shortness of breath
covid-19
  • 15 views
  • 21 Mar, 2021
  • 8 locations
The LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifE

The purpose of this study is to compare the efficacy, safety, and durability of two different strategies to treat participants with a history of sub-optimal adherence and control of their HIV infection: long-acting (LA) antiretroviral therapy (ART) and all-oral standard of care (SOC).

antiretroviral therapy
antiretroviral agents
antibody test
hysterectomy
antiretroviral
  • 266 views
  • 04 Feb, 2022
  • 33 locations
Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

This trial studies the side effects of radiation therapy followed by atezolizumab in treating patients with stage II or III non-small cell lung cancer. Hyperfractionated radiation therapy delivers smaller doses of radiation therapy over time and may kill more tumor cells and have fewer side effects. Immunotherapy with monoclonal antibodies, …

antiretroviral therapy
tubal ligation
major surgery
ct scan
skin cancer
  • 0 views
  • 12 May, 2022
  • 61 locations
Early Feasibility Study on Epios Leads

The Epios early feasibility study aims to explore the uses of novel sub-scalp lead devices in the detection of epileptic seizures. Epios leads are inserted subcutaneously through dedicated tunneling toolkits and have been designed for continuous EEG recording in inpatients. This clinical investigation is part of a stepwise program to …

electrocorticogram
epilepsy monitoring
brain surgery
eeg monitoring
  • 0 views
  • 16 May, 2022
  • 1 location
Ibrutinib + R-CHOP Followed by Ibrutinib Maintenance

This is a prospective, multicenter, single arm, phase II trial in patients with ≥ 18 and <80 years with poor-prognosis (IPI ≥ 2) and newly diagnosed ABC-DLBCL. Aim of the study is to assess the efficacy and the safety of R-CHOP in combination with ibrutinib for 6 cycles followed by …

measurable disease
cancer
gilbert's syndrome
ibrutinib
platelet count
  • 0 views
  • 10 Apr, 2022
  • 33 locations