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Found 75 clinical trials
MEN1611 With Cetuximab in Metastatic Colorectal Cancer (C-PRECISE-01)

Open-label, dose-confirmation and cohort expansion, multicentre, Phase Ib/II study to assess the anti-tumour activity and safety of MEN1611 in combination with cetuximab for the treatment of patients with PIK3CA mutated metastatic colorectal cancer.

fluorouracil
adenocarcinoma
metastasis
irinotecan
cetuximab
  • 2 views
  • 27 Jan, 2021
  • 39 locations
Comparing the Stanford Letter Project Form to Traditional Advance Directives

Our goal is to compare two types of advance directives forms available in English and Spanish to determine which is more easy to use for patients.

  • 0 views
  • 24 Jan, 2021
  • 1 location
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism

The aim of this study is to identify new targets in cholesterol metabolism thanks to a genetically-based strategy.

  • 0 views
  • 24 Jan, 2021
  • 1 location
The Swedish Essential Tremor (SWEET) Trial

To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.

movement disorder
brain stimulation
  • 7 views
  • 23 Jan, 2021
  • 7 locations
S1803 Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first

lenalidomide
daratumumab
induction therapy
heparin
aspirin
  • 86 views
  • 07 Mar, 2021
  • 551 locations
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)

for weekly echoes. Although mothers with low titer anti-Ro will not be continued in Step 2 and therefore not followed by FHRM, birth ECGs will be collected to confirm that low titer antibodies do not

  • 42 views
  • 26 Jan, 2021
  • 32 locations
An Effectiveness-Implementation Trial of SPIRIT in ESRD

called "Sharing Patient's Illness Representation to Increase Trust" (SPIRIT). SPIRIT is a 6-step, 2-session, face-to-face intervention to promote cognitive and emotional preparation for end-of-life

nephropathy
dialysis
  • 74 views
  • 19 Feb, 2021
  • 40 locations
#ChopViolence/#ChopHIV

assessment point) at HBC venues to track trends in violence (i.e., intimate partner, HBC and neighborhood violence), HIV stigma, substance use, mental health, sexual risk and HIV care engagement. In Step 2

  • 0 views
  • 07 Mar, 2021
  • 1 location
Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women

This study will evaluate the safety and efficacy of the long-acting injectable agent cabotegravir (CAB LA) compared to daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for pre-exposure prophylaxis (PrEP) in HIV-uninfected women.

vaccination
local anesthetic
HIV Vaccine
hysterectomy
pre-exposure prophylaxis (prep)
  • 767 views
  • 25 Jan, 2021
  • 22 locations
Very Early Intensive Treatment of HIV-Infected Infants to Achieve HIV Remission

The study will explore the effects of early intensive antiretroviral therapy (ART) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among HIV-infected infants.

antiretroviral therapy
reverse transcriptase inhibitor
hiv antibodies
HIV Vaccine
antibody test
  • 94 views
  • 24 Jan, 2021
  • 49 locations