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Found 90 clinical trials
MEN1611 With Trastuzumab (+/- Fulvestrant) in Metastatic Breast Cancer

The main purpose of this open-label, dose-escalation, phase Ib study is to identify the appropriate dose of MEN1611 to be used in combination with Trastuzumab with/without Fulvestrant for the treatment of advanced or metastatic HER2-positive breast cancer

  • 5 views
  • 25 May, 2021
  • 34 locations
MEN1611 With Cetuximab in Metastatic Colorectal Cancer (C-PRECISE-01)

Open-label, dose-confirmation and cohort expansion, multicentre, Phase Ib/II study to assess the anti-tumour activity and safety of MEN1611 in combination with cetuximab for the treatment of patients with PIK3CA mutated metastatic colorectal cancer.

metastasis
adenocarcinoma
adenocarcinoma of colon
measurable disease
fluorouracil
  • 3 views
  • 27 Jan, 2021
  • 39 locations
Comparing the Stanford Letter Project Form to Traditional Advance Directives

Our goal is to compare two types of advance directives forms available in English and Spanish to determine which is more easy to use for patients.

  • 0 views
  • 24 Jan, 2021
  • 1 location
The Safety and Pharmacokinetics Study of TAKC-02 Inhalation Solution in Healthy Adult Males.

in healthy male subjects. The study is a Single Ascending Dose (Step followed by a Multiple Comparative Dose (Step 2).

  • 0 views
  • 02 Sep, 2021
  • 1 location
A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Moderate to Severe Upper Facial Lines

with moderate to severe Glabellar Lines (GL) Step 2 (Phase II): does finding step in participants with moderate to severe GL Stage 2 (phase II) An evaluation of

  • 0 views
  • 15 Aug, 2021
  • 1 location
Safety and Immunogenicity of a Klebsiella Pneumoniae Tetravalent Bioconjugate Vaccine (Kleb4V)

In this study, the tetravalent bioconjugate candidate vaccine Kleb4V will be tested to obtain first-time-in-human (FTIH) data on its safety and immunogenicity in healthy adults.

  • 0 views
  • 20 Jul, 2021
  • 2 locations
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism

The aim of this study is to identify new targets in cholesterol metabolism thanks to a genetically-based strategy.

  • 0 views
  • 07 Aug, 2021
  • 1 location
The Swedish Essential Tremor (SWEET) Trial

To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.

movement disorder
brain stimulation
  • 7 views
  • 23 Jan, 2021
  • 7 locations
Addressing Drug Use Stigma in HIV Care and Treatment Clinics in Tanzania

The goal of this study is to adapt and pilot an effective health facility HIV stigma-reduction intervention to address drug use stigma in HIV care and treatment clinics (CTCs) in Tanzania, a barrier to linkage and retention in HIV care for people living with HIV (PLWH) who use drugs. In …

  • 0 views
  • 11 Jul, 2021
  • 6 locations
S1803 Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first

aspirin
induction therapy
heparin
daratumumab
lenalidomide
  • 90 views
  • 07 Mar, 2021
  • 551 locations