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Found 137 clinical trials
Intravascular Ultrasound Versus Angiography Guided Drug-coated Balloon Treatment for STEMI Patients a Prospective Multicenter Randomized Controlled Trial

angiography for ST-segment elevated myocardial infarction STEMIpatients. Background: In primary percutaneous coronary intervention for STEMI, DCB angioplasty has proved to be a safe and feasible

  • 24 Jan, 2021
  • 1 location
Safety and Efficacy of Bivalirudin During Short-term Intervention of Non-infarction Related Artery After PPCI of STEMI

This is a randomized, open label, cohort study, in which a total of 100 patients will be enrolled and randomly assigned to receive bivalirudin or heparin in a 1:1 ratio during short-term intervention of non-infarction related artery for acute ST-segment elevation myocardial infarction after emergency percutaneous coronary intervention. NACE, MACE, …

  • 09 May, 2022
  • 1 location
Thrombolysis in STEMI Patients Compared With pPCI on Recanalization Time in the Context of the COVID-19 Outbreak. (RESCUE-STEMI)

During the outbreak of COVID-19, for patients with acute ST-segment elevation myocardial infarction with unclear infection, the time of primary PCI is uncertain, and it is often expected to exceed 90 minutes or even 120 minutes. In indicated patients, intravenous thrombolysis has significantly improved the recanalization time of criminal vessels.

  • 07 Jun, 2022
  • 1 location
Ticagrelor Monotherapy After Stenting (TIMO)

, prospective phase II study 200 patients who undergo coronary artery stenting due to NSTEMI or STEMI will be included. Primary endpoint (variable): The composite of cardiac death, spontaneous

  • 30 Jun, 2022
  • 1 location
Efficacy of an Early Phase Single Bolus r-SAK for Acute Myocardial Infarction: a Multi-center Randomized Clinical Trial

improving myocardial tissue level perfusion, reducing myocardial infarction size, improving cardiac function and clinical prognosis in STEMI patients.

  • 28 Apr, 2022
  • 3 locations
Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Myocardial Infarction

This study is a first-in-human assessment of safety of using UCMSC in patients with AMI via a combination of IC and IV stem cell administration. The novelty of the current UMSC01 treatment study is the dual route of administration. Since dual administration of UCMSC via IC and IV had never …

  • 15 Feb, 2022
  • 1 location
Feasibility Trial Evaluating Efficacy and Safety of Solitaire Thrombus Retrieval Device in the Management of Refractory Thrombus in Patients With Acute Coronary Syndrome

The study is designed as a multicentre open label prospective feasibility trial to capture preliminary efficacy and safety information on Solitaire device to plan an appropriate pivotal study.

  • 27 Jan, 2021
  • 5 locations
Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE

Objective: to evaluate the efficacy and safety of the Recombinant Non-immunogenic Staphylokinase with its single bolus administration in comparison with the bolus-infusion administration of the Alteplase in patients with massive pulmonary embolism

  • 11 Mar, 2022
  • 14 locations
Timing of FFR-guided PCI for Non-IRA in STEMI and MVD (OPTION-STEMI)

Patients with STEMI (ST-segment elevation myocardial infarction) with multivessel disease which have PCI (percutaneous coronary intervention)-suitable non-IRA (infarct related artery) will be

  • 24 Jul, 2022
  • 19 locations
Intravascular Ultrasound Guided PCI in STEMI (iSTEMI)

The purpose of is study is to investigate whether intravascular ultrasound-guided (IVUS) percutaneous coronary intervention (PCI) improve the clinical outcome of patients with ST-segment elevation myocardial infarction treated with primary PCI.

chest pain
percutaneous coronary intervention
left bundle branch block
  • 18 Jun, 2022
  • 1 location