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Found 121 clinical trials
"CAP" Fetge Gras. Lifestyle Modification Program in Catalonia.

produces a significant reduction in liver steatosis and is associated with a higher rate of weight loss compared to standard recommendations currently indicated in Primary Care.

  • 14 Aug, 2021
  • 1 location
TREating Pediatric Obesity

The main aim of the study is to collect preliminary information on the feasibility and efficacy of a time restricted eating intervention in Spanish children and adolescents with obesity and metabolic comorbidities. Two 8-week interventions will performed in a randomized crossover controlled design: a) reduction of the habitual eating window; …

hdl cholesterol
cholesterol level
insulin resistance
LDL Cholesterol
  • 24 Nov, 2021
  • 1 location
An Adaptive Two-Part Phase 2, Multi-Center, Randomized, Double Blind, Placebo-Controlled Study to Assess the Safety, Efficacy, and Pharmacokinetics of Multiple Doses of ION224 Administered Once Monthly in Adult Subjects With Confirmed Non-Alcoholic Steatohepatitis

steatohepatitis (NASH) histologic improvement and to assess the effect on liver steatosis by magnetic resonance imaging-determined proton density fat fraction (MRI-PDFF), additional changes in NASH histologic

  • 20 Sep, 2022
  • 42 locations
Efficacy and Safety of Tocovid Suprabio 200mg in Non-alcoholic Fatty Liver (NAFL)

MRI. Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases ranging from simple fatty liver (steatosis, NAFL) to non-alcoholic steatohepatitis (NASH) to cirrhosis. NASH is the

  • 18 Oct, 2021
  • 4 locations
The Availability of the Enhanced Liver Fibrosis (ELF) Test Affects the Rate of Diagnosis of Nonalcoholic Steatohepatitis (NASH) With Fibrosis in Patients Referred to Hepatology

Background: During the hepatology evaluation, vibration-controlled transient elastography (VCTE) is often used as a clinical decision aid to target high-risk patients for liver biopsy. The enhanced liver fibrosis (ELF) test is expected to be approved in the US. We tested the hypothesis that making the ELF results available to the …

  • 29 May, 2022
  • 1 location
Impact of Exercise Intervention for Patients With Non-alcoholic Fatty Liver Disease (NAFLD)

In Taiwan, with the westernization of eating habit and lifestyle, metabolic syndrome and non-alcoholic fatty liver (NAFLD) have become very important health issues. This project will therefore study the histological and clinical data of patients with non-alcoholic fatty liver disease and explore the impact of exercise intervention on the hepatic …

  • 21 Mar, 2022
  • 1 location
The Effect of Time-restricted Eating on Liver Metabolism

that involves restricting food intake to 6-10 h/day with no energy intake the rest of the day. In rodents, TRE significantly decreases hepatic steatosis and dyslipidemia, while it supports a healthier

body mass index
  • 20 Aug, 2021
  • 1 location
Impact of Time-restricted Feeding in NAFLD (NAFLD-TRF)

. It will be investigated whether TRF improves insulin sensitivity, impacts on metabolic inflammation and reduces liver steatosis.

  • 18 Apr, 2022
Metabolic Effects of Plant-based Diet

The purpose of this study is to assess the metabolic effects of plant based diet on healthy young adults.

Accepts healthy volunteers
  • 12 May, 2022
  • 1 location
Estrogen Administration for the Treatment of NASH in Postmenopausal Women

estrogen deficiency plays an important role in the pathology of steatosis, inflammation and fibrosis in non-alcoholic steatohepatitis (NASH), the progressive form of NAFLD. Post-menopausal women are a

  • 05 May, 2022
  • 1 location