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Found 121 clinical trials
A Prospective Prevalence Study in Adolescent and Adult Patients Dependent on Parenteral Nutrition to Assess the Incidence of Intestinal Failure-Associated Liver Disease (THRIVE-1)

week. Liver disease will be determined by the presence of choline deficiency, cholestasis (confirmed by elevated serum alkaline phosphatase (ALP) liver isoenzyme level), and steatosis (confirmed by

  • 0 views
  • 21 Sep, 2022
  • 7 locations
Bariatric Endoscopy and NAFLD

Find out how bariatric endoscopy will influence the clinical course of non-alcoholic fatty liver disease.

liver disease
  • 0 views
  • 27 May, 2021
  • 1 location
Bariatric Surgery Effect Nonalcoholic Fatty Liver Disease

This is a prospective cohort study, which subjects were obese patients requiring bariatric surgery. The bariatric procedures include laparoscopic sleeve gastrectomy (LSG), laparoscopic Roux-en-Y gastric bypass (LRYGB), and one anastomosis gastric bypass-mini gastric bypass (OAGB-MGB). The main observation is the cure rate of NAFLD:percentage of liver fat content <5% of …

insulin
hemoglobin a1c
insulin resistance
liver disease
MRI
  • 0 views
  • 05 Mar, 2022
  • 1 location
Nonalcoholic Fatty Liver Disease in HIV Database

, cirrhosis, and liver failure. The spectrum of NAFLD encompasses simple nonalcoholic steatosis (nonalcoholic fatty liver [NAFL]) and nonalcoholic steatohepatitis (NASH) in which there is evidence of

  • 0 views
  • 28 Jul, 2022
  • 5 locations
The Visceral Adiposity Measurement and Observation Study (VAMOS)

The Visceral Adiposity Measurement and Observation Study

  • 0 views
  • 09 Aug, 2022
  • 3 locations
Characterization of the Platelet Inflammatory Response in NAFL and NASH

The primary objective of the study is to identify which features of platelet activation promote the inflammatory response that underlies the progression from NAFL to NASH. Therefore, the investigators plan: To characterize and compare the platelet inflammatory phenotype in NAFL vs NASH patients To study if and how the signaling …

  • 0 views
  • 22 Mar, 2022
  • 1 location
Screening Patients With Diabetes Mellitus for the Presence of Skin Disorder of Scleredema

Scleredema is a scleroderma-like skin disorder appearing in 2.5-14% among patients with type 1 or 2 diabetes mellitus. This is a single centre study to screen consecutive patients with diabetes mellitus for the presence of scleredema,and to compare the clinical-laboratory data of patients with and without scleredema. Metabolic and vascular …

diabetes
diabetes mellitus
  • 3 views
  • 03 Mar, 2022
  • 1 location
Alterations of Gut Microbiota and Metabolites in ALD Patients

Alcohol-associated liver disease is one of the most prevalent liver diseases worldwide, and the leading cause of liver transplantation in the U.S. Alcohol-related liver disease is associated with changes in the intestinal microbiota and metabolites.

Accepts healthy volunteers
  • 0 views
  • 23 Jul, 2022
  • 1 location
Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.

  • 0 views
  • 20 Oct, 2021
  • 1 location
Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia

Obstructive sleep apnea (OSA) is a common condition associated with significant adverse health outcomes. Our overarching hypothesis is that patients with OSA and hypoxia (H-OSA) have greater degrees of insulin resistance in both liver and adipose tissue when compared to those without hypoxia (NH-OSA) thus leading to increased risk for …

diabetes
insulin
continuous positive airway pressure
Accepts healthy volunteers
  • 47 views
  • 06 Jun, 2022
  • 1 location