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Found 47 clinical trials
Featured trial
CT COMPARE: CT COronary Angiography to Measure PlAque REduction

The study is investigating how the amount of plaque in your arteries can be reduced by statin medication. Researchers at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland, are looking for volunteers to participate in a 36-month study. There are no costs for study-related tests, procedures or medication. For …

statin therapy
hyperlipidemia
hmg-coa reductase inhibitors
  • 365 views
  • 22 Dec, 2020
  • 1 location
Featured trial
FOURIER - Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk

FOURIER - Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk

  • 270 views
  • 25 Mar, 2021
  • 1 location
A Randomized, Double-blind, Placebo-controlled, Multicenter Trial, Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Participants With Established Cardiovascular Disease (VICTORION-2 PREVENT) (VICTORION-2P)

Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants with established cardiovascular disease (CVD).

  • 1 views
  • 10 Oct, 2022
  • 662 locations
STREAM Trial - Statins in Multimorbid Older Adults Without Cardiovascular Disease (STREAM)

Statins are among the most widely used drugs. While they were found to be effective for primary and secondary prevention of cardiovascular disease (CVD) in middle-aged subjects, their benefits for primary prevention in older adults (aged ≥70 years) without CVD are uncertain, particularly for those with multimorbidity. The aim of …

  • 2 views
  • 04 Oct, 2022
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement - a Randomized Controlled Trial (STARC)

Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery. The focus of this study is, therefore, on patients having surgical aortic valve replacement (with aortotomy) and the development of postoperative atrial fibrillation …

  • 0 views
  • 22 Oct, 2022
  • 1 location
Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD

interventional trial for off label use of high dose atorvastatin 80 mg in intermediate AMD patients and correlate recovery response measured by dark adaptation recovery time with drusen volume reduction measured by SD-OCT

spectral domain optical coherence tomography
drusen
  • 0 views
  • 22 Oct, 2021
  • 1 location
  • 12 views
  • 28 Oct, 2022
  • 39 locations
A BCT Intervention for Physical Activity Among Individuals on Statins

participants on primary prevention statin therapy who are at elevated risk for cardiovascular disease (CVD). The intervention will be comprised of 5 BCTs which have previously shown to be effective on

Accepts healthy volunteers
  • 0 views
  • 27 May, 2022
  • 1 location
A BCT Intervention for Medication Adherence Among Individuals on Statins

participants on primary prevention statin therapy who are at elevated risk for cardiovascular disease (CVD). The intervention will be comprised of 5 BCTs which have previously shown to be effective on

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Citrulline Efficacy to Improve Carbohydrate Metabolism Abnormalities in the Patient Treated With High Doses of Statin (STATIMPROVE)

prevention of cardiovascular disease. However, long-term statin therapy is associated with impaired carbohydrate metabolism and increased risk of developing type 2 diabetes (T2D), particularly in patients

  • 23 views
  • 13 Apr, 2022
  • 1 location