Found 363 clinical trials
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Accepting Seniors
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Accepting adults
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An observational study
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For females only
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Currently Recruiting
Chemotherapy on Methylation Patterns in Breast Tumor Tissue Correlating With Clinical Response and Outcomes
Primary Objectives 1. To identify hypermethylated genes in paired pretreatment breast tumor tissue and plasma samples from locally advanced and metastatic breast cancer patients
- 40 views
- 07 Nov, 2020
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Currently Recruiting
Tumoral Bone Strength Assessment by Numerical Simulation Using Quantitative CT : the MEKANOS Study
Osteolytic bone metastases and myeloma bone lesions are responsible of long bone and vertebral fractures leading to restricted mobility, surgery and medullar compression that severely alter quality of life and that have a huge medico-economic impact. It has been estimated that 50% of the patients with bone metastasis will encounter …
- 1 views
- 23 Jan, 2021
- 11 locations
![[18F] F-GLN by PET/CT in Breast Cancer](/media/imagery/249937.svg)
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Accepting Seniors
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Accepting adults
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10s of participants
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An observational study
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For all genders
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
[18F] F-GLN by PET/CT in Breast Cancer
Patients with known or suspected primary or metastatic breast cancer with one lesion that is 1.5 cm in diameter or greater may be eligible for this study. Patients may participate in this study
- 0 views
- 26 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An observational study
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For all genders
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Imaging of Primary or Recurrent Breast Cancer With 18F-FluorThanatrace PET/CT
Patients with known or suspected, in the opinion of an investigator, primary or metastatic breast cancer may be eligible for this study. Up to 30 evaluable patients will undergo study imaging in
- 0 views
- 25 Jan, 2021
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Accepting Seniors
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Accepting adults
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10s of participants
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An observational study
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For all genders
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Paclitaxel Therapeutic Drug Monitoring in Cancer Patients
The goals of this prospective, observational cohort study are to determine the feasibility of implementing paclitaxel therapeutic drug monitoring for cancer patients and explore the relationship between paclitaxel drug exposure and the development of neuropathic symptoms. This trial studies if paclitaxel can be consistently measured in the blood of patients …
- 0 views
- 28 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For females only
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Currently Recruiting
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
This study gathers information from the blood cells and tumor tissue during treatment with anti-HER2 therapies, such as trastuzumab, pertuzumab, lapatinib, or neratinib, in patients with HER2 positive stage I-IV breast cancer who are scheduled to start anti-HER2 therapy. The information gained from this study may help researchers better understand …
- 0 views
- 25 Jan, 2021
- 1 location
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Multi-country trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Currently Recruiting
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer Moonshot Study
This trial studies the genetic analysis of blood and tissue samples from patients with cancer that has spread to other anatomic sites (advanced) or is no longer responding to treatment. Studying these samples in the laboratory may help doctors to learn how genes affect cancer and how they affect a …
- 38 views
- 16 Feb, 2021
- 111 locations
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Concordance Between Liquid and Tissue Biopsy
Tissue biopsy is a procedure to remove a piece of tissue (sample of cells) from the body to be analyzed in a laboratory, and it is commonly performed to confirm diagnosis of a patient with symptoms of breast cancer recurrence. It may also provide information on tumor markers (hormone receptors, …
- 0 views
- 27 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An observational study
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For females only
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts
The aim is to determine the pharmacological and biochemical association between ribociclib exposure and CYP3A variants in African American/Blacks and Non-Hispanic White patients. The investigators hypothesize that patients treated with ribociclib who are CYP3A5 poor metabolizers may be exposed to higher levels of ribociclib than CYP3A5 intermediate or normal metabolizers. …
- 0 views
- 03 Mar, 2021
- 2 locations
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Accepting Seniors
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Accepting adults
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10s of participants
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An observational study
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For all genders
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Currently Recruiting
A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies
The treatment of breast cancer is determined by its 'receptor (or signal) status'. Receptors are signals present on all cells and if abnormal can drive cancer growth. One of the signals that can drive breast cancer growth is the HER2 receptor/signal. One quarter of all breast cancers are found to …
- 0 views
- 23 Jan, 2021
- 2 locations