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Found 363 clinical trials
Oral Paclitaxel Trial In Recurrent and Metastatic Breast Cancer As 1st Line Therapy

To compare and evaluate the efficacy and safety of Liporaxel solution (oral paclitaxel) and Taxol (IV paclitaxel) on recurrent or metastatic breast cancer.

  • 10 views
  • 23 Jan, 2021
  • 36 locations
Paclitaxel (Phyxol) and Cisplatin as First-line Chemotherapy for Metastatic Breast Cancer

The primary endpoint of this phase II trial is the objective response rate of the stage I (low-dose) regimen. The secondary endpoints include treatment-related toxicity, the change in quality of life, progression free survival and overall survival.

hormone therapy
paclitaxel
immunostimulant
adjuvant chemotherapy
endocrine therapy
  • 18 views
  • 07 Nov, 2020
  • 1 location
UFT/LV Maintenance Vs Observation in Metastatic Breast Cancer Responsive to Chemotherapy

To compare maintenance therapy to observation in metastatic breast cancer patients responding (or stabilized) after 1st-line chemotherapy. Main endpoint is disease-free survival

stage iv breast cancer
  • 7 views
  • 07 Nov, 2020
  • 1 location
An Effective and Compliance Regimen of Paclitaxel Plus Cisplatin to Treat Metastatic Breast Cancer

The primary endpoint of this phase II trial is the objective response rate of the stage I (low-dose) regimen. The secondary endpoints include treatment-related toxicity, the change in quality of life, progression free survival and overall survival. Simon's optimal two-stage design will be used to determine the patient number.

hormone therapy
immunostimulant
adjuvant chemotherapy
endocrine therapy
metastasis
  • 1 views
  • 07 Nov, 2020
  • 1 location
Omic Technologies to Track Resistance to Palbociclib in Metastatic Breast Cancer

This is a monocentric cohort study, prospective and interventional with minimal risks and constraints for advanced breast cancer. The planned interventions are collection of biological samples at different times. The study will aim to do a descriptive analysis of omics profiles evolution (tumor, volatile organic components) over time, before and …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Ketogenic Diet and Chemotherapy in Affecting Recurrence in Patients With Stage IV Breast Cancer

This pilot clinical trial studies how well a ketogenic diet and chemotherapy work in affecting the return of cancer in patients with stage IV breast cancer. Ketogenic diet may be more effective

breast cancer
paclitaxel
tumor cells
  • 9 views
  • 24 Jan, 2021
  • 1 location
Vinorelbine Plus (+) Trastuzumab vs Docetaxel Plus (+) Trastuzumab as 1 Line Treatment for HER2 Positive (+) Metastatic Breast Cancer

In an open-label randomised phase III-trial patients with metastatic HER2-positive breast cancer naive to chemotherapy with normal organ function and WHO performance status

her2/neu-positive breast cancer
vinorelbine
docetaxel
trastuzumab
stage iv breast cancer
  • 32 views
  • 07 Nov, 2020
  • 1 location
[18F]Fluorothymidine (FLT) PET/CT Imaging In Rb+ Metastatic Breast Cancer Patients Undergoing LEE011 And Weekly Paclitaxel Therapy

Patients with a history of metastatic breast cancer who are candidates for participation in the companion therapeutic trial, UPCC 06115 "A Phase I Trial of Ribociclib (LEE011) and Weekly

advanced breast cancer
erbb2
paclitaxel
HER2
  • 5 views
  • 08 Nov, 2020
  • 1 location
Ph3 Study of Exemestane With or Without Entinostat in Chinese Patients With Hormone Receptor-Positive Locally Advanced or Metastatic Breast Cancer

or metastatic breast cancer, who have disease progression on endocrine therapy. Additionallythe safety, tolerability, and PK profile of the treatment combination are evaluated.

hormone therapy
progesterone
immunohistochemistry
metastasis
erbb2
  • 8 views
  • 23 Jan, 2021
  • 1 location
89Zr-atezolizumab PET Scan and Lobular Breast Cancer

lobular breast cancer). Ten patients with lobular metastatic breast cancer, who are included in the GELATO trial at the UMCG, are eligible for the ImaGelato study. All patients will undergo two

  • 0 views
  • 24 Jan, 2021
  • 1 location