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Found 57 clinical trials
Featured trial
Advanced Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer

  • 138 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Advanced Stage Non-small Cell Lung Cancer

Advanced Stage Non-small Cell Lung Cancer

  • 258 views
  • 08 Nov, 2020
  • 1 location
Primary Tumor Resection With EGFR TKI for Stage IV NSCLC

Our project is going to enroll patients with stage IV NSCLC with EGFR mutation and evaluate whether primary tumor resection after receiving the afatinib can prolong survival. This project is

  • 0 views
  • 09 Apr, 2022
  • 2 locations
Durvalumab in Combination With Chemotherapy in Virus-infected Patients With Non-small Cell Lung Cancer

This is a phase II trial of durvalumab in combination of platinum-based chemotherapy. Patients with stage IV Non-Small-Cell-Lung Cancer (NSCLC) with human immunodeficiency virus (HIV) infection

pemetrexed
cancer chemotherapy
lung carcinoma
durvalumab
serum bilirubin level
  • 0 views
  • 02 Jun, 2021
  • 3 locations
Atezolizumab Plus 8 Gy Single-fraction Radiotherapy for Advanced Oligoprogressive NSCLC

diagnosed with advanced (stage IV) NSCLC, irrespective of PD-L1 status, and who have oligoprogressed to both immunotherapy with an anti PD-1 agent (e.g., pembrolizumab or nivolumab) and 1 line of

  • 0 views
  • 13 May, 2022
  • 3 locations
OMEGA, Local Ablative Therapy in Oligometastatic NSCLC (OMEGA)

Oligometastatic lung cancer (OM-NSCLC) seems to be associated with a better prognosis than usual Stage IV non-small cell lung cancer when radical local therapy of all metastatic sites is

metastasis
cancer chemotherapy
EGFR
stage iv non-small cell lung cancer
platinum doublet
  • 0 views
  • 24 Feb, 2022
  • 1 location
Concurrent or Sequential Immunotherapy and Radiation Therapy in Patients With Metastatic Lung Cancer (COSINR)

Trial Design Patients with stage IV non-small cell lung cancer are randomized to nivolumab/ipilimumab plus either sequential or concurrent stereotactic body radiotherapy (SBRT

  • 11 views
  • 21 Mar, 2022
  • 1 location
TKI Followed by Thoracic Radiotherapy for Stage IV EGFR Mutant NSCLC

In this phase II trial with single arm, we aim to investigate the clinical efficacy and toxicity profile of local radiotherapy on all disease sites for EGFR-mutant oligo-metastatic NSCLC (no more than 3 metastatic lesions) who did not experience disease progression after at least 3 months of TKI therapy.

EGFR
  • 0 views
  • 03 Feb, 2022
  • 1 location
A Study of Dabrafenib in Combination With Trametinib in Chinese Patients With BRAF V600E Mutant Metastatic NSCLC

The purpose of this study is to evaluate the safety and efficacy of dabrafenib in combination with trametinib in Chinese patients with BRAF V600E mutation-positive metastatic Non-Small Cell Lung Cancer. The general study design has been discussed and agreed with Chinese Health Authority and is applying a similar design used …

metastasis
BRAF
secondary malignant neoplasm of liver
cancer chemotherapy
growth factor
  • 6 views
  • 22 Dec, 2021
  • 1 location
A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line Treatment (CodeBreaK201)

The main objective of this study is to evaluate the tumor objective response rate (ORR) assessed by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria in participants who receive sotorasib at either 960 mg daily or 240 mg daily whose tumors are programmed death-ligand 1 (PD-L1) Tumor Proportion Score …

brain metastases
KRAS
STK11
measurable disease
LKB1
  • 0 views
  • 01 May, 2022
  • 44 locations