Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 50 clinical trials
featured
Advanced Colorectal or Lung Cancer Screening

Advanced Colorectal or Lung Cancer Screening

  • 158 views
  • 25 Mar, 2021
  • 1 location
Phase II Study of Maintenance Capecitabine to Treat Resectable Colorectal Cancer

chemotherapy followed by maintenance therapy with capecitabine to see the efficacy and safety, then to investigate the effect of maintenance therapy for stage IIIC or R0 resected stage IV colorectal cancer

platelet count
adenocarcinoma
adenocarcinoma of colon
adjuvant therapy
capecitabine
  • 16 views
  • 08 Nov, 2020
  • 1 location
Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer

This trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself. The participants in this trial have HER2-positive (HER2+) metastatic colorectal cancer (mCRC). 'Metastatic' means that the cancer has spread to other parts of the body. In the first part of this study, …

irinotecan
monoclonal antibodies
fluorouracil
bevacizumab
adenocarcinoma
  • 308 views
  • 09 May, 2021
  • 80 locations
Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

The main goal of this phase of the study is to determine if objectively assessed Physical Activity (PA) levels in advanced-cancer patients are associated with health care provider (HCP)-assessed ECOG performance status and overall survival. The purpose is to advance the evidence-base for incorporating objective assessment of Physical Activity (PA) …

cyst
radiation oncology
metastasis
cavity
neuroendocrine tumor
  • 43 views
  • 18 Feb, 2021
  • 1 location
Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer

This phase II clinical trial studies how well panitumumab with or without trametinib works in treating patients with stage IV colorectal cancer. Immunotherapy with monoclonal antibodies, such as

  • 20 views
  • 23 Jan, 2021
  • 2 locations
Study of Folfiri/Cetuximab in FcGammaRIIIa V/V Stage IV Colorectal Cancer Patients

Patients' selection thorough the identification of predictive factors still represent a challenge in metastatic colorectal cancer (mCRC). Cetuximab (Erbitux), a chimeric monoclonal antibody binding to the Epidermal Growth Factor Receptor (EGFR), belongs to the Immunoglobulins (Ig) grade 1 subclass able to elicit both in vitro and in vivo the Antibody-Dependent …

irinotecan
monoclonal antibodies
colorectal adenocarcinoma
cetuximab
adenocarcinoma
  • 0 views
  • 25 Jan, 2021
  • 1 location
Phase 1b Study to Evaluate ATP128 With or Without BI 754091 in Patients With Stage IV Colorectal Cancer

cytologically confirmed stage IV colorectal cancer coming form three different patient populations: Cohort 1a: 6 patients with stage IV colorectal cancer (CRC) having failed standard of care (SoC

irinotecan
systemic therapy
neuropathy
cancer
measurable disease
  • 12 views
  • 13 Feb, 2021
  • 6 locations
  • 0 views
  • 24 Jan, 2021
  • 1 location
Impact of Aerobic Exercise on Immune Response and Side Effects of Cancer Treatments

Aerobic exercise is associated with many benefits in patients with cancer treatments. Among these, the reduction of cancer-related fatigue (CRF) is one of the best demonstrated. Besides, several animal models have shown a marked reduction in tumor growth with aerobic exercise, sometimes by more than 60%. As the level of …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer

The investigators hypothesize that intermittent first-line Panitumumab plus FOLFIRI is effective as the same regimen given continuously, in unresectable metastatic RAS and BRAF wild type colorectal cancer patients. Correlative studies on tumor and blood samples could identify potential biomarkers of efficacy and help defining personalized treatment strategy.

  • 0 views
  • 25 Jan, 2021