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Found 21 clinical trials
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CALGB 80702: A Phase III trial of 6 versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer.

CALGB 80702: A Phase III trial of 6 versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer.

  • 124 views
  • 08 Nov, 2020
  • 1 location
Cytokine-induced Killer Cell Immunotherapy for Surgical Resected Stage III Colorectal Cancer Patients After Chemotherapy

We hypothesize through this randomized, prospective, single center adjuvant study, that cytokine-induced killer cell in patients with stage III colon cancer can improve survival in this

  • 11 views
  • 08 Nov, 2020
  • 1 location
LEAn Body Mass Normalization of OXaliplatin Based Chemotherapy

Cytotoxic chemotherapy is usually scaled to the body surface area (BSA), and is currently not adjusted to the body proportions of lean and fat (i.e. body composition) of individual patients. Patients with low muscle mass behave like patients "overdosed" with chemotherapy resulted in dose-limiting toxicities (e.g. dose reductions, treatment delays …

  • 3 views
  • 24 Jan, 2021
  • 1 location
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and

combination chemotherapy
pulmonary disease
platelet count
metastasis
antifungal agents
  • 1047 views
  • 13 May, 2021
  • 575 locations
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

alone for patients who have undergone treatment for high-risk stage II or stage III colon cancer.

exercise intervention
fatigue
cancer treatment
cancer
fatigue assessment and management
  • 397 views
  • 19 Apr, 2021
  • 51 locations
IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting

, folinic acid, 5-FU (mFOLFOX 6) chemotherapy protocols in patients with high-risk stage III colon cancer in the adjuvant setting.

  • 116 views
  • 24 Jan, 2021
  • 27 locations
Adjuvant Aspirin Treatment for Colon Cancer Patients

Following complete resection of their primary tumor, potentially eligible stage II or stage III colon cancer patients will undergo central PIK3CA testing. Patients with somatic mutations will be

PIK3CA
stage iii colon cancer
adenocarcinoma
adenocarcinoma of colon
adjuvant chemotherapy
  • 193 views
  • 26 Jan, 2021
  • 86 locations
FOLFOX or CAPOX Perioperative Chemotherapy Versus Postoperative Chemotherapy for Locally Advanced Colon Cancer (OPTICAL)

BACKGROUND In patients with high risk stage II and stage III colon cancer (CC), curative surgery followed by adjuvant chemotherapy with FOLFOX or CAPOX regimens

folfox regimen
metastasis
stage iii colon cancer
adenocarcinoma
adenocarcinoma of colon
  • 43 views
  • 23 Jan, 2021
  • 1 location
Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over

chemotherapy has demonstrated a benefit on disease-free survival and overall survival after a stage III colon cancer resection. Nevertheless adjuvant chemotherapy is poorly used in elderly patients. Prognostic

capecitabine
colon cancer
fluoropyrimidine
stage iii colon cancer
oxaliplatin
  • 31 views
  • 24 Jan, 2021
  • 203 locations
Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer

This trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself. The participants in this trial have HER2-positive (HER2+) metastatic colorectal cancer (mCRC). 'Metastatic' means that the cancer has spread to other parts of the body. In the first part of this study, …

irinotecan
monoclonal antibodies
fluorouracil
bevacizumab
adenocarcinoma
  • 308 views
  • 09 May, 2021
  • 80 locations