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Found 56 clinical trials
Heterogeneity of Neointimal Healing Following Biodegradable-polymer Drug-Eluting Coronary Stent Implantation

The objective of this study is a comparative evaluation of Orsiro stent and of Resolute Integrity stent in terms of the extent of neointima formation at 4 months after implantation using optical coherence tomography (OCT).

optical coherence tomography
stable angina
angina pectoris
percutaneous coronary intervention
  • 25 Jan, 2021
  • 1 location
HeartHome: A Nurse-Driven Home-Based Cardiac Rehabilitation Program

The purpose of this implementation trial is to execute a nurse-led, home-based cardiac rehabilitation (HBCR) program, evaluate the program's impact on patient outcomes over 6 months; and compare outcomes of HeartHome (HH) participants to a group of participants in traditional cardiac rehabilitation (CR).

cardiac rehabilitation
acute coronary syndrome
myocardial infarction
  • 23 Jan, 2021
  • 1 location
BuqitongluO Granule for Qi Deficiency and Blood Stasis Syndrome

The main purpose of this trial is to evaluate the efficacy and safety of Buqitongluo Granule in treating qi deficiency and blood stasis syndrome, and explore the effect of the improvement of qi deficiency and blood stasis syndrome on the prognosis of diseases.

  • 08 Apr, 2021
  • 1 location
Allopurinol in Patients With Refractory Angina to Improve Ischemic Symptoms

Despite numerous advances in medical treatment and revascularization procedures for the treatment of patients with stable angina, debilitating symptoms that are unresponsive to conventional

  • 07 Mar, 2021
  • 1 location
Morphological Parameters of In-stent RESTenosis Assessed and Identified by OCT

clinical features involving stable angina and acute coronary syndrome. The coronary artery involved will be routinely studied by OCT for a mechanical cause of the intrastent restenosis. The routine use of

  • 07 Mar, 2021
  • 28 locations
FANTOM ENCORE Sirolimus-eluting Bioresorbable Scaffold for Treatment of De-novo CAD: the ENCORE-I Study

Prospective, multicentre, non-randomized, investigator-initiated study aiming to assess the safety and efficacy of the Fantom Encore sirolimus-eluting bioresorbable scaffold (BRS).

  • 25 Jan, 2021
  • 3 locations
Impact of Acarbose on Abnormal Glucose Regulation in Patients With Coronary Artery Disease (AAA Trial)

The objective of this trial is to investigate the effect of early treatment of glucose toxicity with acarbose, a drug to control postprandial hyperglycemia, on the occurence of cardiovascular events and the inhibition of atherosclerosis.

coronary disease
arterial disease
  • 07 Nov, 2020
  • 1 location
Very Long Versus Overlapping Stents in Long Coronary Lesions

This study is performed to compare the angiographic and clinical outcomes of the use of single long stent versus overlapping stents in the treatment of long coronary lesions in patients with chronic coronary syndrome.

  • 13 Feb, 2021
  • 2 locations
Usefulness of the Use of Co-registration Strategy With iFR in Long and/or Diffuse Coronary Lesions

Randomized controlled trial to determinate if the physiological iFR pullback evaluation with Syncvision software (intervention group) could be useful in the reduction of stent length implanted, with the potencial benefit in terms of MACEs reduction at follow-up with respect to angiographic guiding of percutaneous coronary intervention (control group).

  • 24 Jan, 2021
  • 1 location
Near-infrared Spectroscopy Guided Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction

The aim of this study is to investigate whether near-infrared guided percutaneous coronary intervention in patients with acute myocardial infarction provides improved stent strut coverage at six months compared to conventionally angiography guided percutaneous coronary intervention.

  • 08 Mar, 2021
  • 1 location