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Found 58 clinical trials
Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina

This is a multi-center, double-blind, randomized, placebo-controlled, parallel-group phase 3 clinical study to confirm the safety and efficacy of T89 in patients with stable angina pectoris

  • 0 views
  • 27 Jan, 2021
  • 1 location
Safety and Efficacy of Low Temperature Rota-flush Solution in Patients With Severe Calcified Lesion (LOTA-II)

reported that 58 consecutive patients with stable angina requiring PCI with RA to a calcified coronary lesion have 68% 5-fold increase in high sensitivity troponin after RA. The objective of this

troponin
single coronary artery
  • 0 views
  • 12 Sep, 2021
  • 9 locations
Cost-effectiveness and Safety of the CADScorSystem in Patients With Symptoms Suggestive of Stable Coronary Artery Disease.

This study evaluates the addition of the CADScorSystem to a standard Diamond-Forrester score guided rule-out strategy in ambulatory patients referred with symptoms suggestive of stable coronary artery disease. Half of the patients will undergo stratification using a Diamond-Forrester score only, while the other half will undergo stratification using a Diamond-Forrester …

myocardial infarction
artery disease
infarct
  • 0 views
  • 23 Jan, 2021
  • 7 locations
Genotyping GUided Antiplatelet theRapy in pAtieNts Treated With Drug Eluting stEnts (GUARANTEE)

The aim of this study is to assess the efficacy and safety of the CYP2C19 genotype guided antiplatelet treatment strategy, using clopidogrel in non-carriers of a CYP2C19*2 or 3 allele and ticagrelor in carriers of a CYP2C192 or *3 allele in patients treated with new generation drug eluting stents.

artery disease
antiplatelet therapy
ticagrelor
percutaneous coronary intervention
clopidogrel
  • 1 views
  • 27 Jan, 2021
  • 12 locations
Edoxaban Versus Edoxaban With antiPlatelet Agent In Patients With Atrial Fibrillation and Chronic Stable Coronary Artery Disease

This study evaluates the efficacy and safety of Edoxaban with the combination of edoxaban and antiplatelet in patients with stable CAD (coronary artery stenosis 50% on medical treatment or revascularized stable CAD [ 12 months for acute coronary syndrome and 6 months after stable CAD]) and high-risk atrial fibrillation (CHA2DS2-VASc …

vascular disease
coronary artery bypass graft
percutaneous coronary intervention
coronary artery bypass
stenosis
  • 45 views
  • 27 Aug, 2021
  • 14 locations
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial

(DAPT) for these stent systems still needs to be established. With a 2x2 factorial design for patients of stable angina or silent ischemia, the investigators formulate a head-to-head randomized

sirolimus
antiplatelet therapy
infarct
angina pectoris
stenosis
  • 0 views
  • 21 Jan, 2021
  • 7 locations
Effect of Remote Intervention in Patients With SCAD

The study was a multicenter, two-arm, parallel, open-label, prospective clinical trial that evaluated a remote intervention with 1 year of follow-up.

cardiomyopathy
secondary prevention
cardiac rehabilitation
rehabilitation therapy
heart disease
  • 0 views
  • 09 Aug, 2021
  • 1 location
Angiographic Control vs. Ischemia-driven Management of Patients Treated With PCI on Left Main With Drug-eluting Stents

The present study aims to compare a planned angiographic control (PAC) follow-up strategy vs. conservative management for patients treated with drug-eluting stents on unprotected left main artery in a prospective, randomized setting. PAC will be performed by coronary computed tomography (CCT), to avoid the limitations of the invasive coronary angiography …

revascularisation
angiography
ischemia
  • 3 views
  • 23 Jan, 2021
  • 4 locations
iCorMicA - Stratified Medicine in Angina

The iCorMicA study is a multicentre, prospective, randomised, double-blind, sham-controlled, parallel-group, end-point trial and registry. The investigators seek to determine whether stratified medical therapy guided by an adjunctive interventional diagnostic procedure (IDP) during the invasive management of patients with known or suspected angina but no obstructive coronary artery disease improves …

  • 0 views
  • 27 Jan, 2021
  • 2 locations
The Flash FFR Study

The overall purpose of Flash FFR is to investigate whether coronary angiography-derived fractional flow reserve (caFFR), compared with fractional flow reserve (FFR) measured by a pressure wire, has non-inferior clinical effect and cost benefit in guiding the percutaneous coronary intervention (PCI) for patients with moderate coronary artery stenosis in terms …

  • 0 views
  • 30 Jan, 2021
  • 1 location