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Found 124 clinical trials
Trial of Nivolumab and Cetuximab After Chemoradiation in Esophageal Squamous Cell Carcinoma Patients.

squamous cell carcinoma patients. Subjects must have received no prior treatment for esophageal cancer (chemotherapy, radiotherapy or surgery) and no prior treatment with checkpoint inhibitors.

pet-ct scan
esophageal cancer
endoscopic ultrasound
chemotherapy regimen
cetuximab
  • 4 views
  • 24 Feb, 2022
  • 1 location
Pre-Operative Pembrolizumab + Chemoradiation in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma

To investigate the safety and activity of preoperative pembrolizumab combined with chemoradiotherapy for resectable esophageal squamous cell carcinoma (ESCC) ,20 patients enrolled in Phase Ib

pembrolizumab
chemoradiotherapy
squamous cell carcinoma
carcinoma
  • 6 views
  • 05 Sep, 2021
  • 2 locations
A Randomized Controlled Trial Evaluating of Prophylactic Irradiation in CRT for cT1bN0M0 ESCC (ARMADILLO)

This study is conducted to investigate whether modified chemoradiotherapy with elective nodal irradiation reduces the locoregional recurrence that cannot be completely resected by salvage endoscopic resection and preserve esophagus without compromising overall survival.

endoscopy
esophageal cancer
chemotherapy regimen
chemoradiotherapy
cancer
  • 0 views
  • 25 Apr, 2022
  • 1 location
Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002) (KEYSTONE-002)

, compared with neoadjuvant chemoradiotherapy and surgery for locally advanced ESCC in multicenter.

esophageal cancer
chemotherapy regimen
adjuvant therapy
pembrolizumab
chemoradiotherapy
  • 2 views
  • 13 Jun, 2022
  • 1 location
A Study of Perioperative Camrelizumab Combined With Chemotherapy in Patients With Resectable ESCC

The purpose of this study is to observe and evaluate the efficacy and safety of camrelizumab combined with albumin paclitaxel and cisplatin as perioperative treatment of advanced esophageal squamous cell.

immunomodulator
paclitaxel
carcinoma
neutrophil count
blood cell count
  • 0 views
  • 30 May, 2022
  • 1 location
Neoadjuvant Therapy With Nab-paclitaxel and Cisplatin for Locally Advanced Esophageal Squamous Cell Carcinoma (NTNC)

To verify the role of nab-paclitaxel in neoadjuvant therapy for esophageal squamous cell carcinoma, the investigators designed a prospective, randomized, controlled , multicente phase II trial

renal function
aptt
esophageal cancer
chemotherapy regimen
cancer
  • 0 views
  • 15 Feb, 2022
  • 1 location
Carrelizumab Chemotherapy and Apatinib in the Neoadjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma

other treatments were continuously improved, however, the mortality of esophageal squamous cell carcinoma patients was not significantly decreased. For patients with locally advanced esophageal

  • 0 views
  • 26 Jan, 2021
  • 1 location
Z650 in Advanced Esophageal Squamous Cell Carcinoma With EGFR Over Expression or Gene Amplification

The purpose of this study is to evaluate the safety and efficacy of Z650 in Advanced Esophageal Squamous Cell Carcinoma patients With EGFR Over expression or Gene Amplification.

measurable disease
EGFR
carcinoma
chemotherapy regimen
squamous cell carcinoma
  • 0 views
  • 16 May, 2022
  • 1 location
A Prospective, Single-arm Phase Ib/II Study to Explore the Safety and Efficacy of Pembrolizumab Combined With Neoadjuvant Chemoradiotherapy (CRT) Followed by Surgery for Upper Locally Advanced Esophageal Squamous Cell Carcinoma (ESCC)

Through a prospective, single-center, single-arm, phase Ib/II study, we aim to explore the safety and feasibility of a new treatment mode for upper esophageal cancer, which is that pembrolizumab combined with chemoradiotherapy as neoadjuvant therapy and then followed by radical surgery.

  • 0 views
  • 11 Oct, 2022
  • 1 location
Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma

The aim of this study is to investigate the effect of postoperative concurrent chemoradiotherapy versus radiotherapy alone for patients with locally advanced esophageal squamous cell carcinoma

docetaxel
chemoradiotherapy
metastasis
carcinoma
esophageal carcinoma
  • 7 views
  • 05 Mar, 2022
  • 4 locations