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Found 124 clinical trials
A Study of Camrelizumab Combined With Chemotherapy as Neoadjuvant Therapy in Adcanced Esophageal Squamous Cell Carcinoma (ESCC)

To evaluate the efficacy and safety of camrelizumab combined with albumin paclitaxel and platinum chemotherapy in the preoperative treatment of locally advanced thoracic esophageal squamous cell

  • 0 views
  • 28 Feb, 2021
  • 1 location
PET Imaging-guided Chemoradiotherapy in Esophageal Squamous Cell Carcinoma

response (cCR) in patients with unresectable esophageal squamous cell carcinoma (ESCC).

  • 0 views
  • 29 Mar, 2021
  • 1 location
Chemoradiation Plus Tislelizumab for Conversion Therapy of Locally Nonresectable ESCC (LATE)

nonresectable ESCC.

chemotherapy regimen
neutrophil count
carboplatin
adjuvant therapy
platelet count
  • 0 views
  • 08 Jun, 2022
  • 1 location
Comparing Paclitaxel/Cisplatin and Cisplatin/5-fluorouracil in Neo-CRT for ESCC

This clinical trial has two stages: phase II and phase III. Eligible patients will be randomized 1:1 to the two arms: paclitaxel plus cisplatin and cisplatin plus 5-fluorouracil. The phase II stage will enroll 128 patients, 64 patients for each arm. The endpoint of the phase II stage is complete …

chemotherapy regimen
esophageal squamous cell carcinoma
kidney function test
cancer
ct scan
  • 3 views
  • 15 Jun, 2022
  • 1 location
Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma (ASSURE)

This is a randomized noninferiority multicenter trial. Patients will be stratified according to the participating hospital. Patients will be randomized to one of the treatment arms. Arm A: Patients will receive surgical resection, including Ivor Lewis esophagectomy or McKeown esophagectomy and systematic lymphadenectomy. Arm B: Patients will receive 5-fluorouracil (5-FU) …

squamous cell carcinoma of esophagus
kidney function test
esophageal carcinoma
ct scan
carcinoma
  • 5 views
  • 28 May, 2022
  • 5 locations
Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC (iCROSS)

chemoradiotherapy followed by minimally invasive esophagectomy for locally advanced resectable esophageal squamous cell carcinoma (cII-III Stage) patient.

chemotherapy regimen
kidney function test
carcinoma
squamous cell carcinoma
esophagectomy
  • 0 views
  • 10 Jul, 2022
  • 1 location
Conversion of Tislelizumab Combined With Chemotherapy in Unresectable Esophageal Squamous Cell Carcinoma

prospective, single-center, single-arm phase II clinical study of the safety and efficacy of tislelizumab combined with chemotherapy in the treatment of unresectable esophageal squamous cell carcinoma.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
Moderately Hypofractionated Conformal Radiation Combined With S-1 for Esophageal Squamous Cell Carcinoma

This Phase II randomized study is to determine the efficacy and toxicities of moderately hypofractionated conformal radiation combined With S-1 for esophageal squamous cell carcinoma.

kidney function test
ct scan
renal function
carcinoma
squamous cell carcinoma
  • 2 views
  • 13 Feb, 2022
  • 1 location
Pembrolizumab Plus Paclitaxel Cisplatin Followed by Surgery for Locally Advanced ESCC (KEYSTONE-001)

esophageal squamous cell carcinoma.

squamous cell carcinoma
endoscopic ultrasound
pembrolizumab
paclitaxel
carcinoma
  • 0 views
  • 04 Apr, 2021
  • 1 location
Combination of Toripalimab and Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

cell death receptor-1PD-1 /programmed cell death-Ligand 1(PD-L1) checkpoints has demonstrated promising activity in ESCC. In Keynote181 study, for patients with metastatic esophageal squamous cell

  • 0 views
  • 27 Jan, 2021
  • 1 location