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Found 365 clinical trials
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Advanced Head and Neck Squamous Cell Carcinoma

People with head and neck squamous cell carcinoma may be eligible to participate in a research study being conducted by Northwell Health.  

cavities
cancer
  • 55 views
  • 27 Jan, 2021
  • 1 location
featured
A Phase II, Multi-Center, Single-Arm, Global Study of MEDI4736 Monotherapy in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

A Phase II, Multi-Center, Single-Arm, Global Study of MEDI4736 Monotherapy in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

  • 612 views
  • 08 Nov, 2020
  • 1 location
  • 22 views
  • 27 Jan, 2021
  • 42 locations
A Study of ASP1951 in Subjects With Advanced Solid Tumors

The primary purpose of this study is to evaluate the tolerability and safety profile of ASP1951 when administered as a single agent and in combination with pembrolizumab in participants with locally advanced (unresectable) or metastatic solid tumors; characterize the pharmacokinetic profile of ASP1951 when administered as a single agent and …

  • 23 views
  • 12 Jun, 2021
  • 24 locations
A Study of ASP1948 Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l Inhibitor (Nivolumab or Pembrolizumab) in Subjects With Advanced Solid Tumors

The purpose of this study is to evaluate the tolerability and safety profile of ASP1948 when administered as a single agent and in combination with nivolumab or pembrolizumab in participants with locally advanced (unresectable) or metastatic solid tumors; characterize the pharmacokinetic profile of ASP1948 when administered as a single agent …

  • 75 views
  • 02 Jun, 2021
  • 56 locations
Radiotherapy With Double Checkpoint Blockade of Locally Advanced HNSCC

First-line treatment of locally advanced HNSCC with double checkpoint blockade and radiotherapy dependent on intratumoral CD8+ T cell Infiltration.

  • 0 views
  • 13 Jun, 2021
  • 14 locations
Docetaxel and Loplatin Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced SCCHN

combined with cisplatin chemoradiotherapy in the treatment of locally advanced head and neck squamous cell carcinoma.

  • 3 views
  • 21 Jan, 2021
  • 1 location
Circulating Tumor Cells as an Early Predictive head-and -Neck Squamous-cell Carcinoma

In France, the incidence of head and neck squamous cell carcinomas (HNSCC) is 16 000 new cases/year. During these last years, many new chemotherapies and targeted therapies have been developed

  • 1 views
  • 08 Nov, 2020
Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging

Known risk factors inducing squamous cell carcinomas of the head and neck are tabacco and alcohol intake. However, the incidence of human papillomavirus (HPV) related oropharyngeal carcinomas is increasing. It is known that HPV+ and HPV- tumors have a different reaction to (chemo)radiotherapy. The exact mechanisms underlying these differences is …

squamous cell carcinoma of the head and neck
chemoradiotherapy
human papillomavirus
carcinoma
ct scan
  • 0 views
  • 23 Jan, 2021
  • 1 location
Intensity-Modulated Radiation Therapy & Nivolumab for Recurrent or Second Primary Head & Neck Squamous Cell Cancer

This phase II trial studies how well intensity-modulated radiotherapy and nivolumab work together in treating patients with head and neck squamous cell cancer that has come back. Intensity-modulation radiation therapy uses varying intensities of radiation beams to kill cancer cells and shrink tumors, thereby reducing the damage to nearby healthy …

  • 10 views
  • 11 Mar, 2021
  • 4 locations