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Found 130 clinical trials
Trial of Docetaxel Cisplatin Fluorouracil (5-FU) for Unresectable Advanced Esophageal Squamous Cell Carcinoma (ESCC)

This phase I/II study is being conducted to determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and efficacy of a combination chemotherapy using docetaxel, cisplatin and 5-fluorouracil (DCF) in unresectable advanced esophageal cancer. The usefulness of the this regimen is evaluated by RECIST, time to progression and median survival time.

measurable disease
carcinoma
recurrent esophageal cancer
fluorouracil
squamous cell carcinoma
  • 9 views
  • 07 Nov, 2020
  • 1 location
Local Therapy for Oligorecurrent and Oligometastatic Esophageal Squamous Cell Carcinoma

squamous cell carcinoma led to significant improvements in progression-free survival (PFS).

  • 0 views
  • 02 May, 2021
  • 1 location
Neoadjuvant CCRT With/Without Bevacizumab for Locally Advanced ESCC

Esophageal squamous cell carcinoma (ESCC) is one of the ten leading cancers in Taiwanese male. The prognosis is poor with a five-year overall survival rate of 10 to 30 %. Randomized clinical

  • 0 views
  • 23 Jan, 2021
  • 1 location
Camrelizumab Combined With Radiotherapy for Adjuvant Treatment of Esophageal Squamous Cell Carcinoma After Surgery

This is an investigator-initiated, single-arm, single-center, exploratory clinical study.The study population consisted of patients with R0 resection of esophageal squamous cell carcinoma who

  • 0 views
  • 13 Feb, 2021
  • 1 location
Toripalimab or Placebo With Paclitaxel and Cisplatin in Esophageal Squamous Cell Carcinoma

and cisplatin(TP regimen )with placebo combined with TP regimen in patients with advanced or metastatic Esophageal Squamous Cell Carcinoma(ESCC )who have not received systemic chemotherapy previously

  • 0 views
  • 25 Jan, 2021
  • 1 location
A Phase III Study of Nimotuzumab Plus Concurrent Chemoradiotherapy in Loco-regional Esophageal Squamous Cell Carcinoma

suggested synergy between nimotuzumab, paclitaxel, cisplatin and radiation. For our phase II study in locally advanced esophageal squamous cell carcinoma (ESCC), the combination of cetuximab and

  • 0 views
  • 21 Jan, 2021
  • 12 locations
Sintilimab Injection Combined With Concurrent CCRT in Locally Advanced Esophageal Squamous Cell Carcinoma

This study evaluated the effectiveness and safety of sintilimab combined with cCRT in patients with locally advanced ESCC.

  • 0 views
  • 25 Jan, 2021
  • 1 location
Study of Neo-adjuvant Chemoradiotherapy Followed by Minimally Invasive Esophagectomy for Squamous Cell Esophageal Cancer

The primary objective is to compare neo-adjuvant chemoradiotherapy followed by Mckeown Minimally Invasive Esophagectomy (MIE) Versus Mckeown MIE, pure radical chemoradiotherapy in terms of the overall survival time (OS) in patients with Stage IIB or III squamous cell esophageal carcinoma.

  • 26 views
  • 08 Nov, 2020
  • 1 location
Toripalimab With Paclitaxel and Cisplatin as Neoadjuvant Treatment for Esophageal Squamous Cell Carcinoma

this study was to evaluate the efficacy and safety of toripalimab, an anti-PD-1 antibody, combined with paclitaxel and cisplatin as neoadjuvant treatment in local advanced esophageal squamous cell

  • 0 views
  • 25 Mar, 2021
  • 1 location
The Phase II Trial of SHR-1210 Combined With Preoperative Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

The purpose of this study is to observe and evaluate the efficacy and safety of SHR-1210 combined with preoperative chemotherapy for locally advanced esophageal squamous cell carcinoma

  • 0 views
  • 25 Jan, 2021
  • 1 location