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Found 152 clinical trials
A Study of the Change in Early and Sustained Pain Control in Radiographic Axial Spondylarthritis in Adult Participants Receiving Upadacitinib (UPSTAND)

Axial spondyloarthritis (axSpA) is an immune-mediated inflammatory disease primarily affecting the axial skeleton. The most frequent axSpA symptom is chronic, often inflammatory back pain (IBP

  • 7 views
  • 26 May, 2022
  • 61 locations
Evolution and Treatments of Chronic Inflammatory Systemic Diseases (MISTIC)

are inflammatory bowel diseases (IBD - Crohn's disease [MC] and ulcerative colitis [RCH]), and chronic inflammatory rheumatic diseases (rheumatoid arthritis [RA] and spondyloarthritis [SpA] including

ulceration
colitis
psoriatic arthritis
arthritis
rheumatism
  • 0 views
  • 25 Feb, 2022
  • 1 location
Observational Study in Patients Treated With JAK Inhibitors for Inflammatory Rheumatism (MAJIK)

Janus kinase (JAK) inhibitors are a new class of molecules available to the therapeutic arsenal for chronic inflammatory rheumatic diseases.The tolerance profile of this new class needs to be better defined and its use in real life further established. The French Society of Rheumatologists intends to coordinate a prospective national …

biological drug
rheumatism
rheumatoid arthritis
psoriatic arthritis
rheumatic diseases
  • 0 views
  • 05 Aug, 2021
  • 56 locations
Pregnancy and Medically Assisted Conception in Rare Diseases

Rare diseases frequently affect women of childbearing age. Pregnancy in these women has become less rare, but remains associated with high levels of complications. One obstacle to their optimal management during pregnancy is that there are no prospective studies of pregnancy during rare diseases and several connective tissue diseases. As …

rare diseases
scleroderma
connective tissue disorder
antiphospholipid syndrome
systemic disease
  • 239 views
  • 13 May, 2021
  • 2 locations
Italian Registry of Arthritis on Biologic Therapy (GISEA)

clinical data of patients with rheumatoid arthritis and spondyloarthritis beginning a treatment with biologic drugs in order to assess the long-term safety and efficacy in the real life.

sulfasalazine
tumor necrosis factor alpha
methotrexate
psoriatic arthritis
ankylosing spondylitis
  • 7 views
  • 01 Mar, 2022
  • 1 location
Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic Diseases

Introduction: The medical treatment of inflammatory rheumatic diseases has improved dramatically during the last decades primarily due to the introduction of biological disease modifying anti-rheumatic drugs (bDMARDs). However, bDMARD treatment failure occurs in 30-40% of patients due to lack of effectiveness or side effects. The tools to predict treatment outcomes …

rheumatoid arthritis
psoriatic arthritis
connective tissue disorder
arthritis
anti-rheumatic drugs
  • 286 views
  • 24 Jan, 2021
  • 12 locations
AR-Power Patient Powered Research Network

participate in research from participants with rheumatoid arthritis (RA), spondyloarthritis (SpA), and other musculoskeletal conditions. Participants will provide information from their smartphones or

  • 15 views
  • 23 Jan, 2021
  • 1 location
Comparative Effectiveness and Safety of Biosimilar and Legacy Drugs

In Canada and worldwide there is a need for updated independent real-world comparative effectiveness and safety data related to biologic drugs including biosimilar drugs. Biosimilar drugs hold potential to improve access to needed therapies at reduced cost enabling savings to be reallocated to other needs. However updated real-world evidence on …

intestinal diseases
tumor necrosis factor alpha
biosimilar
tumor necrosis factor
inflammatory bowel disease
  • 3 views
  • 25 Jan, 2021
  • 1 location
Genetic Analysis to Predict the Development of Paget's Disease (GAPDPD)

Paget's disease of the bone (PDB) is a skeletal disorder with a strong genetic component which can be associated with various complications such as pain, bone deformity, arthritis and deafness. Recent advances in understanding the genetic determinants of PDB offer the prospect of developing a genetic profiling test which can …

blood test
Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 1 location
Intensity of Physical Activity Level During Daily Living: Unravelling Its Relationship With Chronic Musculoskeletal Disorders and Evaluating Underlying Facilitators and Barriers, An Exploratory Survey Study (MSK-SUR)

chronic musculoskeletal disorders (CMDs) are a hugh burden to healthcare wordwide. Physical activity can improve outcomes related with CMDs, however dose response relationships are poorly understood. Therefore, to date it has not been possible to formulate general recommendations on optimal therapeutic quantity of physical activity. Furthermore, a complexity of possible …

  • 0 views
  • 25 Mar, 2022
  • 1 location