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Found 144 clinical trials
A Study of the Efficacy and Safety of Secukinumab 300 mg in Patients With Thyroid Eye Disease (TED) (ORBIT)

monoclonal anti-IL-17A antibody currently approved for the treatment of 3 inflammatory/ autoimmune diseases: moderate to severe plaque psoriasis (PsO), psoriatic arthritis (PsA), and axial spondyloarthritis

  • 0 views
  • 24 Jul, 2022
  • 6 locations
Treatment With Leflunomide in Patients With Polymyalgia Rheumatica (PMRLEFRCT)

Over the last decades outcome has greatly improved for rheumatoid arthritis (RA) and spondyloarthritis (SpA). This is in sharp contrast to the situation for polymyalgia rheumatica (PMR), with a

arthritis
prednisolone
leflunomide 20 mg
tumor necrosis factor alpha
polymyalgia
  • 228 views
  • 09 Feb, 2022
  • 2 locations
Comparison of Two Electrotherapy Methods on Chronic Low Back Pain

The purpose of this study is; to compare the effects of interferential current therapy (IF) applied in addition to conventional physical therapy on pain, functional status and quality of life compared to pulsed electromagnetic field therapy (PEMF) in patients with chronic low back pain.

back pain
  • 0 views
  • 24 Mar, 2022
  • 1 location
Effects of Cervicothoracic Mobility Program on Low Back Pain

The study will be a randomized control trial to determine the effects of the cervicothoracic mobility program on pain, range of motion, and function in patients with chronic back pain. The purposive sampling technique will be used. A sample of 44 patients will be taken and divided into two groups …

low back pain
back pain
  • 0 views
  • 20 Jun, 2022
  • 1 location
Testing of a New Therapeutic Vibration Device to Reduce Neuromuscular Weakness in Hospitalized Patients

Objective: Test the ability of vibration to produce physiologic, biochemical, and anatomic changes consistent with exercise that would help prevent the development of muscle weakness that occurs when patients are immobile for long periods of time.

Accepts healthy volunteers
  • 0 views
  • 15 Jun, 2022
  • 1 location
A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice (PsABIOnd)

The purpose of this study is to evaluate treatment persistence with guselkumab and interleukin-17 inhibitor (IL-17i) initiated at enrollment into this study (PsABIOnd).

DMARD
biological drug
anti-rheumatic drugs
  • 6 views
  • 26 Jul, 2022
  • 34 locations
Advanced Sensor Based Functional ASsessmenTs in Axial Spondyloarthritis

This is an observational study using Inertial Measurement Unit (IMU) sensors to measure the effects of biological therapy on spinal mobility and function in axial spondyloarthritis. Participants

MRI Scan
biological therapy
  • 0 views
  • 16 Oct, 2021
  • 1 location
Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls

Hereditary hypophosphatemia (XLH) is a rare, inherited disease. Loss-of-function mutation in the phosphate regulating gene with homologies to endopeptidases on the X-chromosome (PHEX) results in excess fibroblast growth factor 23 (FGF23) production and manifests as rickets in children and osteomalacia in adults. This study aims to characterize and measure pain, …

Accepts healthy volunteers
  • 3 views
  • 23 Mar, 2022
  • 1 location
German Spondyloarthritis Inception Cohort

The German Spondyloarthritis Inception cohort (GESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in Germany on patients with early SpA including ankylosing

spondyloarthropathy
arthritis
uveitis
psoriasis
crohn's disease
  • 42 views
  • 22 Oct, 2021
  • 1 location
Natural History and Development of Spondyloarthritis

Background Spondyloarthritis (SpA) is a group of bone and joint disorders that may cause back and joint pain and stiffness. In some cases, SpA can lead to abnormal

arthritis
Accepts healthy volunteers
stiffness
arthralgia
spondyloarthropathy
  • 288 views
  • 28 Jul, 2022
  • 1 location