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Found 144 clinical trials
Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation (GO-GUT)

The hypothesis of the study is that the presence of (subclinical) gut inflammation at baseline in patients with early active axial spondyloarthritis predisposes to a more severe disease defined

back pain
remission
hla-b27
factor a
tumor necrosis factor
  • 3 views
  • 03 Feb, 2022
  • 3 locations
Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Trials

, unacceptable side effects among individual patients with axial spondyloarthritis (AxSpA),to compare selective COX-2 and nonselective COX inhibitors impact on Health related Quality of Life (HrQOL) and how this

  • 0 views
  • 08 Mar, 2022
  • 1 location
Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

This randomized pragmatic trial will generate knowledge about strategies used to de-escalate tumor necrosis factor inhibitor (TNFi) therapy in patients with juvenile spondyloarthritis with

  • 0 views
  • 08 Jan, 2022
  • 1 location
Effects of Nonsteroidal Anti-Inflammatory Drugs in Recurrence of Spondyloarthritis Patients After Remission

The multicenter, randomized controlled trial is to investigate and evaluate the effect of NSAIDs therapy on recurrence in patients with axial spondyloarthritis;

remission
renal function
NSAID
steroidal anti-inflammatory drugs
  • 1 views
  • 03 May, 2022
  • 1 location
Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (ELEFTA)

active radiographic axial spondyloarthritis (axSpA). The study will include HLA-B27+ patients with radiographic axSpA who had no response to prior therapy with Non-steroidal anti-inflammatory drugs

  • 0 views
  • 22 Jul, 2022
  • 2 locations
ABY-035 in the Treatment of Subjects With Ankylosing Spondylitis

regimens of ABY-035 and clinical response as assessed by Assessment of Spondyloarthritis International Society 40 (ASAS40) response at Week 16 in subjects with active AS.

x-rays
NSAID
  • 0 views
  • 05 Apr, 2022
Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis

clinical studies including healthy subjects and patients with psoriasis and psoriatic arthritis and is currently being studied in uveitis, axial spondyloarthritis and hidradenitis suppurativa. This study

angiography
prednisone
corticosteroids
fluorescein angiography
retinal vascular
  • 11 views
  • 10 Aug, 2022
  • 3 locations
Abatacept Bone Effects in Psoriatic Arthritis With Bone Biomarker

Observation has pointed out, that osteitis present in the MRI scans, predicts bone erosion and that this in accordance with the concept by underlining the importance of bone marrow involvement in arthritis [Krabben A, 2013]. Abatacept with its favourable safety profile preferentially interrupts activation of nave T cells and perhaps …

  • 2 views
  • 24 Jan, 2021
A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) (CHERISH)

The purpose of the study is to assess systemic certolizumab pegol (CZP) exposure, the formation of anti-CZP antibodies and safety of CZP across the course of pregnancy in study participants with chronic inflammatory diseases.

tuberculosis
certolizumab pegol
interferon gamma release assay
bacillus calmette-guerin
cimzia
  • 68 views
  • 30 Jun, 2022
  • 10 locations
Monitoring Spondyloarthritis With SpA-Net (TeleSpA)

versus standard care for patients with spondyloarthritis.

Accepts healthy volunteers
  • 0 views
  • 25 Apr, 2022
  • 1 location