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Found 29 clinical trials
Eltrombopag Combining Rituximab Versus Eltrombopag in the Management of Primary Immune Thrombocytopenia (ITP) in Adults

conducted in adult ITP patients who had not responded to or had relapsed after previous treatment of ITP, including first line therapy and /or splenectomy.

  • 0 views
  • 25 Jan, 2021
  • 1 location
Distal Pancreatectomy Minimally Invasive or Open for Malignancy (DIPLOMA)

with splenectomy because of proven or highly suspected PDAC. Intervention: Minimally invasive distal pancreatectomy (either laparoscopic or robot-assisted) Control: Open distal

pdac
cancer
  • 0 views
  • 28 Oct, 2021
  • 5 locations
Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients

Persons without a spleen are susceptible to potentially lethal infections from certain bacteria, with pneumococcus being the most prevalent. Vaccines are provided to help protect against these infections, though they do not so with certainty. Trauma patients who sustain an injury to their spleen currently have three treatment options available …

  • 1 views
  • 23 Mar, 2022
  • 1 location
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis (PACIFICA)

This study (study ID PAC203 North America; PAC303 ex-North America) is evaluating 200 mg BID of pacritinib compared to physician's choice (P/C) therapy in patients with MF and severe thrombocytopenia (platelet count <50,000/μL). Approximately 348 patients in total will be enrolled, randomized 2:1 to either pacritinib (approximately 232 patients) or …

left upper quadrant pain
neutrophil count
myelofibrosis
platelet count
pacritinib
  • 698 views
  • 23 Apr, 2022
  • 74 locations
Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)

The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion …

coronary artery bypass graft
cancer
stroke
angina pectoris
vascular surgical procedures
  • 12 views
  • 12 Apr, 2022
  • 14 locations
Vagus Nerve-guided Robotic-assisted Splenectomy and Azygoportal Disconnection (VNRSD)

This study aimed to evaluate whether vagus nerve-guided robotic-assisted splenectomy and azygoportal disconnection is effective and safe, and to determine whether a reduction in the incidence of

  • 0 views
  • 11 May, 2022
  • 1 location
Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection (ESAPT)

The purpose of this study is to determine whether Apixaban is effective and safe in Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients after Laparoscopic Splenectomy and

  • 0 views
  • 09 May, 2022
  • 1 location
  • 0 views
  • 19 Apr, 2022
  • 1 location
The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients (ELSL)

In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy. To determine whether

splenectomy
  • 0 views
  • 29 Apr, 2022
  • 1 location
The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients (ELSDL)

In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal

splenectomy
  • 0 views
  • 29 Apr, 2022
  • 1 location