Found 45 clinical trials
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is a unique Registry-Randomized Clinical Trial
- 46 views
- 06 Jan, 2020
- 119 locations
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease
dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require dialysis. It works by blocking a hormone (aldosterone) in your body that causes
- 41 views
- 05 Nov, 2020
- 98 locations
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Phase 4 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
ACEI/CCB Versus ACEI/DIU Combination Antihypertensive Therapy in Chinese Hypertensive Patients (ACvAD)
Study name: ACEI/CCB versus ACEI/DIU combination antihypertensive therapy in Chinese hypertensive patients (ACvAD) Medicine: Benazepril 10 mg / amlodipine besylate 5 mg fixed-dose combination, benazepril 10 mg / hydrochlorothiazide 12.5 mg fixed-dose combination. Rationale:Most hypertension guidelines, including the Chinese guidelines for hypertension, recommend the combination of angiotensin-converting enzyme inhibitors (ACEI) …
- 8 views
- 08 Nov, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Hepatology (Liver, Pancreatic, Gall Bladder)
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Currently Recruiting
Spironolactone After Liver Transplant
To study spironolactone to prevent CNI kidney injury.
- 16 views
- 08 Nov, 2020
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Spironolactone for Paroxysmal Atrial Fibrillation
To determine whether or not spironolactone can prevent or delay the occurrence of atrial fibrillation.
- 4 views
- 07 Nov, 2020
- 1 location
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Phase 1 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For males only
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Currently Recruiting
Spironolactone Versus Prednisolone in DMD
This is a randomized, open-label, pilot clinical trial of spironolactone suspension versus oral prednisolone for use in Duchenne muscular dystrophy. The goals are to determine the safety of 6
- 36 views
- 24 Feb, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
Cardiovascular Protective Effect of Spironolactone in Hemodialysis
The purpose of the present study is to determine if spironolactone is safe and effective in the treatment of cardiovascular complications in hemodialysis patients.
- 57 views
- 07 Nov, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Aldosterone in Diabetic Nephropathy
The purpose of this study is to determine whether spironolactone are effective in the reduction of albuminuria and diastolic disfunction of subjects with diabetic nephropathy.
- 29 views
- 07 Nov, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis Trial
, slowly progressive and cumulative, resulting in heart attack, stroke and/or death and blockage of arteries. This study is being done to assess the effectiveness of Spironolactone therapy to slow
- 49 views
- 08 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Adrenal Artery Ablation for Uncontrolled Hypertension
have to take spironolactone or other antihypertensive drugs for long time. On the other side, long-term inhibition of aldosterone receptor may cause hyperkalemia, male breast hyperplasia and other
- 0 views
- 08 Nov, 2020
- 1 location