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Found 134 clinical trials
A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD (TRITON)

The purpose of this study is to compare CHF 5993 with CHF 1535 in improving lung function, reducing moderate and severe COPD exacerbations, and other clinical efficacy and safety outcomes in the target subject population.

  • 08 Jun, 2022
  • 8 locations
A Coping Skills Program for Children With Asthma

Uncontrolled asthma in school-aged children is a significant public health problem. Latino children living in low-income contexts are at increased risk for uncontrolled asthma compared to non-Latino white children, and stress is an unaddressed factor in this disparity. Therefore, the purpose of the current study is to test an intervention …

  • 21 Apr, 2022
  • 1 location
A Phase 2 Study of Daratumumab Subcutaneous (Dara-SC) Administration in Combination With Carfilzomib and Dexamethasone (DKd) Compared With Carfilzomib and Dexamethasone (Kd) in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab to Evaluate Daratumumab Retreatment

The purpose of this study is to compare the efficacy (rate of very good partial response [VGPR] or better as best response as defined by the International Myeloma Working Group [IMWG] criteria) of daratumumab subcutaneous (Dara-SC) in combination with carfilzomib and dexamethasone (Kd) with the efficacy of Kd in participants …

cell transplantation
refractory multiple myeloma
progressive disease
  • 21 Oct, 2022
  • 110 locations
Pulmonary Function Using Non-invasive Forced Oscillometry (PUFFOR)

The purpose of this observational study is to measure pulmonary function in term and preterm infants with and without pulmonary disease including respiratory distress syndrome, bronchopulmonary dysplasia, transient tachypnea of the newborn, meconium aspiration syndrome, and response to treatments given to newborn infants with lung diseases using a non-invasive airway …

transient tachypnea of the newborn
bronchopulmonary dysplasia
respiratory distress
pulmonary disease
transient tachypnea of newborn
  • 05 Apr, 2022
  • 1 location
Preoperative and Postoperative Incentive Spirometry in Patients Undergoing Major Abdominal Surgery

The goal of this study is to determine the efficacy of incentive spirometry (IS) to improve pulmonary function in the preoperative and postoperative surgical setting. The investigators

  • 25 May, 2022
  • 1 location
Asthma Diagnosis Verified by Lung Function

is CE-marked and provides doctors and nurses with information on patient spirometry incl. reversibility test and diurnal or weekly variability of PEF in relation perceived symptoms. Thereby, digital

  • 27 Jan, 2021
  • 1 location
Breathing Room Intervention to Achieve Better Lung Health in Older Adults

of this pilot is to examine the effect of Breathing Room on inspiratory muscle strength, spirometry confirmed ventilatory function (Forced Expiratory Volume in one second (FEV1), Forced Vital

Accepts healthy volunteers
  • 29 Apr, 2022
  • 1 location
Thoracic Mobility in Cystic Fibrosis Care

spirometry examinations. b / A prospective, consecutive cross-sectional study of the same cohort. The aim is to investigate the extent of stiffness and pain that is examined standardized (number of

  • 30 Jan, 2021
  • 1 location
E-monitoring of PULMonary Function in Patients With Duchenne Muscular Dystrophy at Home" (E-PULMoDMD)

. This study aimed to investigate whether it is possible to monitor pulmonary function at home by using an individual electronical spirometry system in children with Duchenne muscular dystrophy DMD. The

duchenne muscular dystrophy
respiratory assessment
  • 07 Oct, 2022
  • 1 location
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

oxide as surrogate markers of inflammation. For comparison purposes, spirometry and measurements of exhaled nitric oxide will also be obtained if possible during a naturally occurring exacerbation of

  • 25 Jan, 2021
  • 1 location