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Found 261 clinical trials
Pulmonary Assessment in Thoracic Insufficiency Syndrome Patients

with spine disorders such as scoliosis. The inability of the thorax to support normal respiration or lung growth can cause respiratory distress and even mortality. Investigators aim to validate MRI

  • 05 Aug, 2021
  • 1 location
The Effect of Intrawound Vancomycin Powder in Spine Surgery

Problem: Postoperative wound infection following various spinal surgeries is a serious complication. The incidence of post-surgical wounds in spine surgery is high, and various researchers have reported different infection rates. In addition, increased healthcare costs, prolonged lengths of stay in hospital, and reduced quality of life as a result of …

  • 16 May, 2022
  • 2 locations
Mazor X Stealth Versus O-arm Navigation for Pedicle Screw Insertion (RGNV)

The investigators would like to investigate the fluoro-registered Mazor X Stealth in terms of pedicle screw accuracy and radiation exposure in comparison with the O-arm and navigation as the institutional gold standard.

  • 21 Mar, 2022
  • 1 location
Cognitive Behavioral Therapy (CBT) After Lumbar Spinal Fusion in Patients With High Pain Catastrophizing (TRIBECA)

Catastrophizing has emerged as the strongest independent predictor for persistent postsurgical pain. Although behavioral interventions, including Cognitive Behavioral Therapy (CBT), have been shown to reduce the impact of persistent pain, postsurgical patients have not historically been offered these interventions. The aim of our study is to examine whether an intervention …

leg pain
disc disease
spinal fusion
behavioral therapy
  • 28 Feb, 2022
  • 1 location
Evaluation of the Influence of Deep Brain Stimulation on the Spinal Deformities Associated With Parkinson's Disease

The intention of the study is to investigate whether Deep Brain Stimulation (DBS) will improve postural deformities of patients with Parkinson's disease.

brain stimulation
deep brain stimulation
  • 25 Jan, 2022
Improving Spine Surgical Care With Real-Time Objective Patient Tracking Using the Apple Watch

One of the primary goals of spine surgery is to reduce pain and increase mobility to improve patients' quality of life. Currently, there is no established method for surgeons to objectively track their patients' mobilization postoperatively. This study is the first prospective trial utilizing the Apple Watch to objectively track …

spine surgery
  • 12 Jun, 2021
  • 1 location
Preventing Curve Progression and the Need for Bracing in Adolescent Idiopathic Scoliosis With Calcium + Vitamin D Supplementation

There is an association between adolescent idiopathic scoliosis (AIS) and low bone mass which has been reported to be a significant prognostic factor for curve progression. Given that dietary calcium (Ca) intake and serum Vit-D levels were also low in AIS, we therefore propose a randomized double-blinded placebo-controlled trial to …

  • 14 Feb, 2022
  • 1 location
Optimization of a Tool for Predicting Postoperative Clinical Evolution After Lumbar Surgery (DeepSurgery)

The objective of the study is the establishment, optimization and prospective evaluation of a digital predictive platform capable of providing for each lumbar spine operated patient a clinical predictive status: Patient green (success) orange (treatment failure ), red patient (complication) in order to optimize his medical care up to 6 …

  • 05 Apr, 2022
  • 2 locations
Opioid Free Anesthesia and Major Spine Surgery

This study compares the intraoperative opioid free anesthesia approach in multilevel spine posterior instrumentation surgery to a conventional opioid-based anesthesia. Half of participants will receive opioid free anesthesia with dexmedetomidine, lidocaine and ketamine while the other half will receive opioid based anesthesia with fentanyl, remi-fentanyl and ketamine

spine surgery
postoperative pain
  • 21 Mar, 2022
  • 1 location
Vertebral Body Tethering Treatment for Idiopathic Scoliosis

This study will determine whether vertebral body tethering is a safe and feasible method of treatment for pediatric idiopathic scoliosis.

idiopathic scoliosis
anterior vertebral body tethering
spina bifida
  • 13 Feb, 2022
  • 1 location