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Found 614 clinical trials
Evaluation of the Impact of Lesions of the Motor and Proprioceptive Brain and Pan-medullary Pathways on Their Clinically and Electrophysiologically Assessed Function in Multiple Sclerosis (MS-TRACTS)

Multiple Sclerosis (MS) is the most common acquired neurological disease leading to disability, especially ambulatory, in young adults. To date, the correlation between the number or volume of white matter lesions seen on conventional MRI and the degree of disability of patients remains low to moderate. This phenomenon is known …

Accepts healthy volunteers
  • 0 views
  • 26 May, 2022
  • 1 location
Brain Computer Interface: Neuroprosthetic Control of a Motorized Exoskeleton (BCI)

The BCI project falls within the very broad field of brain machine interfaces. Its multiple applications include the compensation of motor deficits. The subject of the present protocol is the first test of the system in man on the compensation of motor deficits by an epidural brain implant enabling an …

  • 23 views
  • 22 Oct, 2022
  • 1 location
Hydroxychloroquine and Indapamide in SPMS

The purpose of this clinical trial is to determine if HCQ in a dose of 400mg daily and indapamide in a dose of 2.5mg daily can help in reducing the progression of disability in people with secondary progressive multiple sclerosis. The number of participants in this study will be 35. …

  • 0 views
  • 25 May, 2022
  • 1 location
Improved Bowel Cleansing Method for Colonoscopy Based on High Risk Population of Bowel Preparation

The purpose of this study is to observe the difference in bowel preparation quality between compound sodium picosulfateCSP combined with lactulose and polyethylene glycol electrolytePEG combined with lactulose in high-risk population.

  • 0 views
  • 07 Oct, 2022
  • 1 location
Interest of Immersive Virtual Reality on Stress During Botulinum Toxin Injections in Spasticity (RVTOX) (RVTOX)

The main objective of the study is to investigate the effect of exposure to a virtual reality session during botulinum toxin injections on injection-induced stress. The secondary objectives are to study the effect of exposure to a virtual reality session during botulinum toxin injections, on the pain induced by the …

  • 0 views
  • 05 Jun, 2022
  • 1 location
Hypofractionated Adjuvant Radiotherapy for Resected Head and Neck Cancers (HART-HN)

The primary purpose of this study is to determine the safe reduction of the treatment fractions to 10, 8, or 5, that may be delivered safely in resected head and neck squamous cell carcinoma (HNSCC) patients with intermediate pathologic risk features.

  • 0 views
  • 21 Mar, 2022
  • 1 location
Sensorimotor Imaging for Brain-Computer Interfaces

The investigators will use fMRI to map movement activity in motor and somatosensory cortex using enriched imagery in people with chronic tetraplegia. The investigators expect that somatotopic organization of movement activity will be preserved in people with upper limb impairments, which can be quantified using the strength, area, and location …

  • 0 views
  • 05 May, 2022
  • 1 location
The Safety/Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-LDP) for Lumbar Discogenic Pain

This experimental use umbilical cord mesenchymal stem cells in treatment of the early stage of lumbar discogenic pain (endogenous pain of the disc) to evaluate its safety and efficacy. This experimental is mainly aimed at over 18years old people, regardless of gender, with refractory and persistent back pain for more …

  • 14 views
  • 21 Mar, 2022
  • 1 location
Wheelchair Maintenance Training Program

The objective of this research study is to assess the effectiveness of a remote wheelchair maintenance training program, and to determine methods which may increase overall success of an online training program.

  • 0 views
  • 07 Oct, 2022
  • 1 location
EC50 of Dexmedetomidine in Deep Brain Stimulation Implantation of Patients With Parkinson's Disease

Dexmedetomidine (DEX) sedation is widely used in deep brain stimulation implantation (DBSI) of patients With Parkinson's disease. However, intraoperative application of DEX may affect the discharge activity of deep brain nuclei and reduce the discharge frequency of Subthalamic nucleus (STN) neurons. At present, there is still a lack of prospective …

brain stimulation
  • 0 views
  • 07 Jul, 2022
  • 1 location